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Twenty-four-hour profiles and sleep-related variations of cortisol, thyrotropin and plasma renin activity in healthy african melanoids

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Abstract

The 24-h hormone profiles have been well documented in caucasians living in a temperate climate, but they have never been examined in melanoid subjects under equatorial conditions, with a 12-h light-dark cycle in a hot climate. To establish normal data for this population, blood samples were taken at 10min intervals over 24 h in five healthy young melanoids living in Abidjan (Ivory Coast). Cortisol and thyroid stimulating hormone (TSH) concentrations and plasma renin activity (PRA) were determined by radio-immunoassay and sleep was registered using polysomnography. Data were compared with results obtained in Strasbourg (France) from six healthy aged-matched caucasians. The 24-h profile of cortisol concentration was similar in both groups, with a 2-h phase advance in the melanoids. Nocturnal fluctuations of PRA, strongly linked to the rapid eye movement-non rapid eye movement (REM-NREM) sleep cycles, occurred in both groups, with higher levels in the caucasians in the last 2 h of sleep along with greater amounts of NREM sleep. After an evening increase in TSH, the sleep onset-related decrease seen in the caucasians was not observed in the melanoids. In both groups, increasing

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References

  • Brabant G, Prank K, Ranft U, Schuermeyer Th, Wagner TOF, Hauser H, Kummer B, Feistner H, Hesch RD, Von zur Mühlen A (1990) Physiological regulation of circadian and pulsatile thyrotropin secretion in normal man and woman. J Clin Endocrinol Metab 70:403–409

    Article  CAS  Google Scholar 

  • Brandenberger G (1992) Endocrine ultradian rhythms during sleep and wakefulness. In: Lloyd D, Rossi EL (eds) Ultradian rhythms in life processes. Springer, Berlin Heidelberg New York, pp 123–138

    Chapter  Google Scholar 

  • Brandenberger G, Follenius M, Muzet A, Ehrhart J, Schieber JP (1985) Ultradian oscillations in plasma renin activity: their relationships to meals and sleep stages. J Clin Endocrinol Metab 61:280–284

    Article  CAS  Google Scholar 

  • Brandenberger G, Follenius M, Simon C, Ehrhart J, Libert JP (1988) Nocturnal oscillations in plasma renin activity and REM NREM sleep cycles in humans: a common regulatory mechanism? Sleep 11:245–250

    Article  Google Scholar 

  • Brandenberger G, Charifi C, Muzet A, Saini J, Simon C, Follenius M (1994) Renin as a biological marker of the NREM-REM sleep cycle: effect of REM sleep suppression. J Sleep Res 3:30–35

    Article  CAS  Google Scholar 

  • Buguet A, Gati R, Soubiran G, Hanniquet AM, Livecchi-Gonnot G, Bittel J (1988) Seasonal changes in circadian rhythms of body temperatures in humans living in a dry tropical climate. Eur J Appl Physiol 58:334–349

    Article  CAS  Google Scholar 

  • Buguet A, Hankourao O, Gati R (1990) Self-estimates of sleep in African students in a dry tropical climate. J Environ Psychol 10:363–369

    Article  Google Scholar 

  • Ekelund LG, Suchindran CM, Karon JM, Mahon RP, Tyroler HA (1990) Black-white differences in exercise blood pressure. Circulation 31:1568–1574

    Article  Google Scholar 

  • Fisher DA, Odell WD (1971) Effect of cold on TSH secretion in man. J Clin Endocrinol Metab 33:859–862

    Article  CAS  Google Scholar 

  • Fisher NDL, Gleason RE, Moore TJ, Williams GH, Hollenberg NK (1994) Regulation of aldosterone secretion in hypertensive blacks. Hypertension 23:179–184

    Article  CAS  Google Scholar 

  • Follenius M, Brandenberger G, Bandespat JJ, Libert JP, Ehrhart J (1991) Nocturnal cortisol release in relation to sleep structure. Sleep 15:21–27

    Article  Google Scholar 

  • Goichot B, Saini J, Brandenberger G, Follenius M (1992) Nocturnal plasma thyrotropcs (TSH) variations are related to slow wave sleep. J Sleep Res 1:186–190

    Article  CAS  Google Scholar 

  • Goichot B, Brandenberger G, Saini J, Wittersheim G, Follenius M (1994) Nycthemeral patterns of thyroid hormones and their relationships with thyrotropin variations and sleep structure. J Endocrinol Invest 17:181–187

    Article  CAS  Google Scholar 

  • Leach C (1991) Non parametric methods for complex data sets. In: Lovie P, Lovie AD (eds) New developments in statistics for psychology and the social siences. BPS Books, London, pp 1–18

    Google Scholar 

  • Mullen PE (1983) Sleep and its interaction with endocrine rhythms. Br J Psychiat 142:215–220

    Article  CAS  Google Scholar 

  • Parker DC, Rossman LG, Pekary AE, Hershman JM (1987) Effect of 64-hour sleep deprivation on the circadian waveform of thyrotropin (TSH): further evidence of sleep-related inhibition of TSH release. J Clin Endocrinol Metab 64:157–161

    Article  CAS  Google Scholar 

  • Pratt JH, Manatunga A, Bloem LJ, Li W (1993) Racial differences in aldosterone excretion: a longitudinal study in children. J Clin Endocrinol Metab 77:1512–1515

    CAS  PubMed  Google Scholar 

  • Rechtschaffen A, Kales A (1968) A manual of standardized terminalogy, techniques and scoring system for sleep stages of human subjects. Public Health Services, US Government, Washington DC

    Google Scholar 

  • Thompson LM, Rubin RT (1993) Neuroendocrine aspects of primary endogenous depression. XIII. Influence of race on differences in hypothalamo-pituitary-adrenal and pituitary-thyroid function between patients and matched controls. Biol Psychiatry 34:893–895

    Article  CAS  Google Scholar 

  • Van Cauter E (1981) Quantitative methods for the analysis of circadian and episodic hormone fluctuations. In: Van Canter E, Copinschi G (eds) Human pituitary hormones: circadian and episodic variations. Martinus Nijhoff, The Hague, pp 1–25

    Chapter  Google Scholar 

  • Van Canter E (1992) Hormonal and metabolic changes during sleep. In: Mendlewicz J, Racagni G (eds) Target receptors for anxiolytics and hypnotics: from molecular pharmacology to therapeutics. International Academy on Biomedical Drug Research. Karger, Basel, pp 95–108

    Google Scholar 

  • Van Cauter E, Refetoff S (1985) Multifactorial control of the 24-hour secretory profiles of pituitary hormones. J Endocrinol Invest 8:381–391

    Article  Google Scholar 

  • Vescei P, Peuke P, Katzy R, Black L (1972) Radioimmunological determination of plasma cortisol. Experientia 8:1104–1106

    Google Scholar 

  • Wallin JD (1986) Hypertension in black patients. Epiderniologic and pathophysiologic considerations. J Clin Hypertens 1:7–12

    Google Scholar 

  • Yanovski JA, Yanovski SZ, Gold PW, Chrousos GP (1993) Differences in the hypothalamic-pituitary-adrenal axis of black and white women. J Clin Endocrinol Metab 77:536–541

    CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Laboratoire de Physiologie et de Psychologie Environnementales CNRS, 21 rue Becquerel, F-67087, Strasbourg Cedex, France

    B. Goichot & G. Brandehberger

  2. Centre de Recherches du Service de Santé des Armées Emile Pardé, B.P. 87, F-38702, La Tronche Cedex, France

    A. Buguet, A. Montmayeur & L. Bourdon

  3. Département d'Explorations Fonctionnelles, Centre Hospitalier et Universitaire de Yopougon, 21 B.P. 632, 21, Abidjan, Ivory Coast

    P. Bogui

  4. Institut de Neurologie Tropicale, 2 rue du Docteur Marcland, F-87025, Limoges Cedex, France

    M. Dumas

Authors
  1. B. Goichot
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  2. G. Brandehberger
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  3. A. Buguet
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  4. A. Montmayeur
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  5. L. Bourdon
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  6. P. Bogui
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  7. M. Dumas
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Goichot, B., Brandehberger, G., Buguet, A. et al. Twenty-four-hour profiles and sleep-related variations of cortisol, thyrotropin and plasma renin activity in healthy african melanoids. Eur J Appl Physiol 70, 220–225 (1995). https://doi.org/10.1007/BF00238567

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  • DOI: https://doi.org/10.1007/BF00238567

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