Abstract
A meta-analysis was used to examine the independent and interactive effects of dietary restriction, endurance exercise training and gender on resting metabolic rate (RMR). Sixty different group means (covering ≈ 650 subjects) were identified from the scientific literature and subjected to meta-analysis techniques. Collectively (i.e., all groups combined), body weight loss was greater (P < 0.05) for men (∼ 18 kg) than for women (∼ 12 kg). There were no statistically significant exercise training or gender effects on RMR during weight loss. Collectively (i.e., all groups combined), dietary restriction resulted in a − 0.59 kJ min−1 (∼ − 12%) decrease in RMR (P < 0.05). When normalized to body weight, RMR was reduced by less than 2% (P < 0.05). These data suggest that exercise training does not differentially affect RMR during diet-induced weight loss. In addition, decreases in resting metabolism appear to be proportional to the loss of the metabolically active tissue.
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References
Ballor DL (1991) Exercise training elevates RMR during moderate but not severe dietary restriction in obese male rats. J Appl Physiol 70:2303–2310
Ballor DL (1990) Effect of dietary restriction and/or exercise on 23-h metabolic rate and body composition in female rats. J Appl Physiol 71:801–806
Ballor DL, Keesey RE (1991) A meta-analysis of the factors affecting exercise-induced changes in body mass, fat mass and fat-free mass in males and females. Int J Obes 15:717–726
Ballor DL, Poehlman ET (1994) Exercise-training enhances fat-free mass preservation during diet-induced weight loss: a meta-analytical finding. Int J Obes 18:35–40
Ballor DL, Tommerup LJ, Thomas DP, Smith DB, Keesey RE (1990) Exercise training attenuates diet-induced reduction in metabolic rate. J Appl Physiol 68:2612–2617
Barrows K, Snook JT (1987) Effect of a high-protein, very-low-calorie diet on resting metabolic metabolism, thyroid hormones, and energy expenditure of obese middle-aged women. Am J Clin Nutr 45:391–398
Belko AZ, Van Loan M, Barbieri TF, Mayclin P (1987) Diet, exercise, weight loss and exercise expenditure in moderately overweight men. Int J Obes 11:93–104
Bessard R, Schutz Y, Jequier E (1983) Energy expenditure and postprandial thermogenesis in obese women before and after weight loss. Am J Clin Nutr 38:680–693
Besten C den, Vansant G, Weststrate JA, Deurenberg P (1988) Resting metabolic rate and diet-induced thermogenesis in abdominal and gluteal-femoral obese women before and after weight reduction. Am J Clin Nutr 47:840–847
Boer JO de, Es AJH van, Roovers LCA, Raaij JMA van, Hautvast JGAJ (1986) Adaptation of energy metabolism of overweight women to low-energy intake, studied with whole-body calorimeters. Am J Clin Nutr 44:585–595
Burgess NS (1991) Effect of a very-low-calorie diet on body composition and resting metabolic rate in obese men and women. J Am Diet Assoc 91:430–434
Dale D van, Saris WHM (1989) Repetitive weight loss and weight regain: effects on weight reduction, resting metabolic rate, and lipolytic activity before and after exercise and/or diet treatment. Am J Clin Nutr 49:409–416
Dale D van, Saris WHM, Schoffelen PFM, Ten Hoor F (1987) Does exercise give additional effect in weight reduction regimens? Int J Obes 11:367–375
Davies HJA, Baird IM, Fowler J, Mills IH, Baillie JE, Rattan S, Howard AN (1989) Metabolic response to low- and very-low-calorie diets. Am J Clin Nutr 49:745–751
Despres JP, Bouchard C, Savard R, Tremblay A, Marcotte M, Theriault G (1984) The effect of a 20-week endurance training program on adipose-tissue morphology and lipolysis in men and women. Metabolism 33:235–239
Donahoe CP, Lin DH, Kirschenbaum DS, Keesey RE (1984) Metabolic consequences of dieting and exercise in the treatment of obesity. J Consult Clin Psychol 52:827–836
Donnelly JE, Pronk NP, Jacobsen DJ, Pronk SJ, Jakicic JM (1991) Effects of a very-low-calorie diet and physical training regimens on body composition and resting metabolic rate in obese females. Am J Clin Nutr 54:56–61.
Dore C, Hesp R, Wilkins D, Garrow JS (1982) Prediction of energy requirements of obese patients after massive weight loss. Hum Nutr Clin Nutr 36C:41–48
Elliot DL, Goldberg L, Kuehl KS, Bennett WM (1989) Sustained depression of resting metabolic rate after massive weight loss. Am J Clin Nutr 49:93–96
Finer N, Swan PC, Mitchell FT (1986) Metabolic rate after massive weight loss in human obesity. Clin Sci 70:395–398
Foster GD, Wadden TA, Feurer ID, Jennings AS, Stunkard AJ, Crosby LO, Ship J, Mullen JL (1990) Controlled trial of the metabolic effects of a very-low-calorie diet: short- and long-term effects. Am J Clin Nutr 51:167–182
Frey-Hewitt B, Vranizan KM, Dreon DM, Wood PD (1990) The effect of weight loss by dieting or exercise on resting metabolic rate in overweight men. Int J Obes 14:327–334
Groot de LCPGM, Es AJH van, Raaij JMA van, Vogt JE, Hautvast JGAJ (1989) Adaptation of energy metabolism of overweight women to alternating and continuous low energy intake. Am J Clin Nutr 50:1314–1323
Groot de LCPGM, Es ARH van, Raaij JMA van, Vogt JE, Hautvast JGAJ (1990) Energy metabolism of overweight women 1 mo and 1 y after an 8-wk slimming period. Am J Clin Nutr 51:578–583
Grossman E, Eshkol A, Rosenthal T (1985) Diet and weight loss: their effect on norepinephrine, renin and aldosterone levels. Int J Obes 9:107–114
Herring JL, Mole PA, Meredith CN, Stern JS (1992) Effect of suspending exercise training on resting metabolic rate in women. Med Sci Sports Exerc 24:59–65
Heymsfield SB, Casper K, Hearn J, Guy D (1989) Rate of weight loss during underfeeding: relation to level of physical activity. Metabolism 38:215–223
Hill JO, Sparling PB, Shields TW, Heller PA (1987) Effects of exercise and food restriction on body composition and metabolic rate in obese women. Am J Clin Nutr 46:622–630
Kayman S, Bruvold W, Stern JS (1990) Maintenance and relapse after weight loss in women: behavioral aspects. Am J Clin Nutr 52:800–807
Keesey RE (1988) The relation between energy expenditure and the body weight set-point: its significance to obesity. In: Burrows GD, Beumont PJV, Casper RC (eds) Handbook of eating disorders, part 2. Elsevier, New York, 87–102
Keesey RE, Corbett SW (1990) Adjustments in daily energy expenditure to caloric restriction and weight loss by adult obese and lean Zucker rats. Int J Obes 14:1079–1084
Keim NL, Barbieri TF, Van Loan MD, Anderson BL (1990) Energy expenditure and physical performance in overweight women: response to training with and without caloric restriction. Metabolism 39:651–658
Kendrick AV, McPeek CK, Young KF (1990) Prediction of the resting energy expenditure of women following 12–18 weeks of very-low-calorie dieting. Ann Sports Med 5:188–123
Keys A, Brozek J, Henschel A, Mickelsen O, Taylor HL (1950) The biology of human starvation, vol 1. University of Minnesota Press, Minneapolis
Kirk RE (1982) Experimental design: Procedures for the behavioral sciences, 2nd edn. Brooks and Cole, Monterey, Calif.
Kleiber M (1947) Body size and metabolic rate. Physiol Rev 15:511–541
Leenen R, Van Der Kooy K, Deurenberg P, Seidell JC, Weststrate JA, Schouten FJM, Hautvast JFAJ (1992) Visceral fat accumulation in obese subjects: relation to energy expenditure and response to weight loss. Am J Physiol 263:E913-E919
Lennon D, Nagle F, Stratman F, Shrago E, Dennis S (1985) Diet and exercise training effects on resting metabolic rate. Int J Obes 9:39–47
Liebel RL, Hirsch J (1984) Diminished energy requirements in reduced-obese patients. Metabolism 33:164–170
Mathieson RA, Walberg JL, Gwazdauskas FC, Hinkle DE, Gregg JM (1986) The effect of varying carbohydrate content of a very-low-calorie diet on resting metabolic rate and thyroid hormones. Metabolism 35:394–398
McGaw B (1988) Meta-analysis. In: Keeves JP (ed) Educational research, methodology, and measurement:an international handbook. Pergamon, New York, pp 678–685
Mole PA (1990) Impact of energy intake and exercise on resting metabolic rate. Sports Med 10:72–87
Nelson KM, Weinsier RL, James LD, Darnell B, Hunter G, Long CL (1992) Effect of weight reduction on resting energy expenditure, substrate utilization, and the thermic effect of food in moderately obese women. Am J Clin Nutr 55:924–33
Nieman DC, Haig JL, De Guia ED, Dizon GP, Register UD (1988) Reducing diet and exercise training effects on resting metabolic rates in mildly obese women. J Sports Med Phys Fitness 28:79–88
Pavlou KN, Whatley JE, Jannace PW, DiBartolomeo JJ, Burrows BA, Duthie EAM, Lerman RH (1989) Physical activity as a supplement to a weight-loss dietary regimen. Am J Clin Nutr 49:1110–1114.
Phinney SD, LaGrange BM, O'Connell M, Danforth E (1988) Effects of aerobic exercise on energy expenditure and nitrogen balance during very low calorie dieting. Metabolism 37:758–765
Poehlman ET (1989) A review: exercise and its influence on resting energy metabolism in man. Med Sci Sports Exerc 21:515–525
Poehlman ET, Tremblay A, Nadeau A, Dussault J, Theriault G, Bouchard C (1986) Heredity and changes in hormones and metabolic rates with short-term training. Am J Physiol 250:E711-E717
Poehlman ET, Danforth E (1991) Endurance training increases resting energy expenditure and sympathetic nervous system activity in older individuals. Am J Physiol 261:E233-E239
Poehlman ET, Melby CL, Goran MI (1991) The impact of exercise and diet restriction on daily energy expenditure. Sports Med 11:78–101
Prentice AM, Goldberg GR, Jebb SA, Black AE, Murgatroyd PR (1991) Physiological responses to slimming. Proc Nutr Soc 50:411–458
Ravussin E, Burnand B, Schutz Y, Jequier E (1985) Energy expenditure before and during energy restriction in obese patients. Am J Clin Nutr 41:753–759
Rumpler VW, Seale JL, Miles CW, Bodwell CE (1991) Energy-intake restriction and diet-composition effects on energy expenditure in men. Am J Clin Nutr 53:430–436
Russell DM, Walker PM, Leiter LA, Sima AA, Tanner WK, Mickle DA, Whitwell J, Marliss EB, Jeejeebhoy KN (1984) Metabolic and structural changes in skeletal muscle during hypocaloric dieting. Am J Clin Mutr 39:503–513
Weigle DS (1988) Contribution of decreased body mass to diminished thermic effect of exercise in reduced-obese men. Int J Obes 12:567–578
Weigle DS, Sande KJ, Iverius PH, Monsen ER, Brunzell JD (1988) Weight loss leads to a marked decrease in nonresting energy expenditure in ambulatory human subjects. Metabolism 37:930–936
Welle SL, Amatruda JM, Forbes GB, Lockwood DH (1984) Resting metabolic rates of obese women after rapid weight loss. J Clin Endocrinol Metabol 59:41–44
Yang ME, Van Itallie TB (1984) Variability in body protein loss during protracted, severe caloric restriction: role of triiodothyronine and other possible determinants. Am J Clin Nutr 40:611–622
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Ballor, D.L., Poehlman, E.T. A meta-analysis of the effects of exercise and/or dietary restriction on resting metabolic rate. Eur J Appl Physiol 71, 535–542 (1995). https://doi.org/10.1007/BF00238557
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DOI: https://doi.org/10.1007/BF00238557
Key words
- Weight loss
- Resting metabolic rate
- Diet
- Exercise training
- Metabolism