Skip to main content
Log in

Iso-frequency 2-DG contours in the inferior colliculus of the awake monkey

  • Published:
Experimental Brain Research Aims and scope Submit manuscript

Summary

Tone bursts produced bands of selective 2-[14C]-deoxyglucose labelling in the inferior colliculus (IC) of the awake monkey. Low tone frequencies produced labelling in dorsal regions and high tone frequencies produced labelling in ventral regions. The position of the bands coincided with the position of a single unit with a characteristic frequency, which was the same as the frequency producing the labelling. These findings indicate that the bands of labelling represent iso-frequency contours in IC. The iso-frequency contours extended across most of the nucleus and were oriented from dorsomedially to ventro-laterally at 20–30° from the horizontal and became more vertical anteriorly. The width of the contours was as narrow as 200 μm, suggesting that the contours might represent 2 or 3 overlapping cellular laminae.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Aitkin LM, Webster WR, Veale JL, Crosby DC (1975) Inferior colliculus. I. Comparison of response properties of neurons in the central, pericentral and external nuclei of the adult cat. J Neurophysiol 38: 1196–1207

    Google Scholar 

  • Berman AL (1968) The brain of the cat. A cytoarchitectonic atlas with stereotaxic coordinates. The University of Wisconsin Press, Madison

    Google Scholar 

  • Fitzpatrick KA (1975) Cellular architecture and topographic organization of the inferior colliculus of the squirrel monkey. J Comp Neurol 164: 185–208

    Google Scholar 

  • Fitzpatrick KA, Imig TJ (1982) Organizations of auditory connections: The primate auditory cortex. In: Woolsey CN (ed) Multiple auditory areas, Vol 3. Humana Press, New Jersey, pp 71–110

    Google Scholar 

  • Geniec P, Morest DK (1971) The neural architecture of the human posterior colliculus. Acta Otolaryngol Suppl 295: 1–33

    Google Scholar 

  • Gallistel CR, Piner CT, Allen TO, Adler NT, Yadin E, Negin M (1982) Computer assisted analysis of 2-DG autoradiographs. Neurosci Behav Revs 6: 409–420

    Google Scholar 

  • Goldberg JM, Moore RY (1967) Ascending projections of the lateral lemniscus in the cat and monkey. J Comp Neurol 129: 143–156

    Google Scholar 

  • Imig TJ, Ruggero MA, Kitzes LM, Javel E, Brugge JF (1977) Organization of auditory cortex in the owl monkey (Aotus trivirgatus). J Comp Neurol 171: 111–128

    Google Scholar 

  • Merzenich MM, Reid MD (1974) Representation of the cochlea in the inferior colliculus of the cat. Brain Res 77: 397–415

    Google Scholar 

  • Morest DK, Oliver DL (1984) The neuronal architecture of the inferior colliculus in the cat: Defining the functional anatomy of the auditory midbrain. J Comp Neurol 222: 209–236

    Google Scholar 

  • Oliver DL, Morest DK (1984) The central nucleus of the inferior colliculus in the cat. J Comp Neurol 222: 237–264

    Google Scholar 

  • Rockel AJ, Jones EG (1973a) The neural organization of the inferior colliculus of the cat. I. The central nucleus. J Comp Neurol 147: 11–60

    Google Scholar 

  • Rockel AJ, Jones EG (1973b) The neural organization of the inferior colliculus in the cat. II. The pericentral nucleus. J Comp Neurol 149: 301–334

    Google Scholar 

  • Ryan A, Miller J (1977) Effects of behavioral performance on single-unit firing patterns in inferior colliculus of the Rhesus monkey. J Neurophysiol 40: 943–956

    Google Scholar 

  • Ryan A, Miller J (1978) Single unit responses in the inferior colliculus of the awake and performing Rhesus monkey. Exp Brain Res 32: 389–407

    Google Scholar 

  • Semple MN, Aitkin LM (1979) Representation of sound frequency and laterality by units in the central nucleus of cat inferior colliculus. J Neurophysiol 42: 1626–1639

    Google Scholar 

  • Servière J, Webster WR, Calford MB (1984) Iso frequency labelling revealed by a combined 2-[14C]-deoxyglucose, electrophysiological and horseradish peroxidase study of the inferior colliculus of the cat. J Comp Neurol (in press)

  • Sokoloff L (1977) Relation between physiological function and energy in the central nervous system. J Neurochem 29: 13–26

    Google Scholar 

  • Sokoloff L (1982) The radioactive deoxyglucose method. In: Agranoff BW, Aprison MH (eds) Advances in Neurochemistry, Vol 4. Plenum Press, New York, pp 1–82

    Google Scholar 

  • Strominger NL (1973) The organization and distribution of the dorsal and intermediate acoustic striae in the Rhesus monkey. J Comp Neurol 147: 209–234

    Google Scholar 

  • Strominger NL (1978) The anatomical organization of the primate auditory pathway. In: Norback CR (ed) Sensory systems of primates. Plenum Press, New York, pp 53–90

    Google Scholar 

  • Strominger NL, Strominger AI (1971) Ascending brain stem projections of the antero-ventral cochlear nucleus in the rhesus monkey. J Comp Neurol 143: 217–242

    Google Scholar 

  • Webster WR, Servière J, Crewther D, Crewther S (1983) Isofrequency contours in the inferior colliculus of the awake monkey: A combined 2-[14C]-deoxyglucose and electrophysiological study. In: Webster WR, Aitkin LM (eds) Mechanisms of hearing. Monash University Press, Clayton, pp 149

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported by research grants from the National Health and Medical Research Council of Australia and the Australian Research Grants Scheme

Rights and permissions

Reprints and permissions

About this article

Cite this article

Webster, W.R., Servière, J., Crewther, D. et al. Iso-frequency 2-DG contours in the inferior colliculus of the awake monkey. Exp Brain Res 56, 425–437 (1984). https://doi.org/10.1007/BF00237983

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00237983

Key words

Navigation