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Summary

This investigation provides an insight into the physiological changes produced, and processes operating, during and after a typical interval exercise training regime. The role of interval exercise in the modulation of the plasma concentration of sex hormone binding globulin (SHBG) and the hormones β-oestradiol, testosterone, prolactin and growth hormone was assessed. Eight trained male athletes [mean maximal oxygen uptake (\(\dot V\)O2max 64.3 (SD 3.8) ml·kg−1·min−1, mean age 31.5 (SD 4.5) years] undertook an intense interval exercise (treadmill running) protocol to exhaustion. Subjects completed an average of 15.6×1-min runs. This interval protocol produced significant increase in the plasma concentration of SHBG and all four hormones (all P<0.01) in the immediate post-test period. The plasma concentration of the hormones increased as indicated: β-oestradiol (45%), testosterone (38%), prolactin (230%), growth hormone (2000%). These hormones have an established capacity to interact with components of many physiological systems and, as such, may provide a mechanism for the changes induced by intense exercise in many of these systems.

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References

  • Aldercreutz H, Harkonen M, Kuoppasalmi K, Kosunen K, Naveri H, Rehunen S (1976) Physical activity and hormones. Adv Cardiol 18:144–157

    Google Scholar 

  • Anderson DC (1974) Sex hormone binding globulin. Clin Endocrinol 3:69–96

    Google Scholar 

  • Ben-Jonathan N (1985) Dopamine: a PRL inhibiting hormone. Endocr Rev 6:564–589

    Google Scholar 

  • Brisson GR, Ledoux M, Peronnet F, Dulac S, Decarufel D, Volle MA, Rainvillet J, Audet A (1981) Prolactinemia in exercising male athletes. Horm Res 15:218–223

    Google Scholar 

  • Brisson GR, Peronnet F, Ledoux M, Pellerin-Massicotte J, Matton P, Garceau F, Boisvert P (1986) Temperature-induced hyperprolactinemia during exercise. Horm Metab Res 18:283–284

    Google Scholar 

  • Brown WJ, McGinley R, Vining RF, White S (1980) The effect of endurance exercise on the serum concentrations of estradiol and testosterone in trained and untrained men and women. Proc Aust Physiol Pharmacol Soc 11:131

    Google Scholar 

  • Bunt JC, Boileau RA, Bahr JM, Nelson RA (1986) Sex and training differences in human growth hormone levels during prolonged exercise. J Appl Physiol 61:1796–1801

    Google Scholar 

  • Elias AN, Wilson AF, Pandian MR, Chune G, Utsumi A, Kayaleh R, Stone SC (1991) Corticotropin releasing hormone and gonadotropin secretion in physically active males after acute exercise. Eur J Appl Physiol 62:171–174

    Google Scholar 

  • Farrell PA, Garthwaite TL, Gustafson AB (1983) Plasma adrenocortical and cortisol responses to submaximal and exhaustive exercise. J Appl Physiol 55:1441–1444

    Google Scholar 

  • Gala RD (1991) Prolactin and growth hormone in the regulation of the immune system. Proc Soc Exp Biol Med 198:513–527

    Google Scholar 

  • Galbo H (1983) Hormonal and metabolic adaptations to exercise. Thieme, New York

    Google Scholar 

  • Galbo H, Hummer L, Petersen IB, Christensen NJ, Bie N (1977) Thyroid and testicular hormone responses to graded and prolonged exercise in man. Eur J Appl Physiol 36:101–106

    Google Scholar 

  • Ganong WIT (1983) Review of medical physiology (11th edn.). Lange, Los Altos, pp 330, 336–369

    Google Scholar 

  • Godsland IF, Wynn V, Crook D, Miller NE (1987) Sex, plasma lipoproteins and atherosclerosis: prevailing assumptions and outstanding questions. Am Heart J 114:1467–1503

    Google Scholar 

  • Grossmann CJ (1984) Regulation of the immune system by sex steroids. Endocr Rev 5:435–455

    Google Scholar 

  • Hahn AG, Pang PM, Tumilty DMcA, Telford RD (1988) General and specific aerobic power of elite marathon kayakers and canoeists. Excel 5:14–19

    Google Scholar 

  • Jansson G (1991) Oestrogen-induced enhancement of myeloperoxidase activity in human polymorphonuclear leukocytes — a possible cause of oxidative stress in inflammatory cells. Free Radic Res Comm 14:195–208

    Google Scholar 

  • Jurkowski JE, Jones NL, Walker WC, Younglai EV, Sutton JR (1978) Ovarian hormone responses to exercise. J Appl Physiol 44:109–114

    Google Scholar 

  • Karagiorgos A, Garcia J, Brooks GA (1979) Growth hormone response to continuous and intermittent exercise. Med Sci Sports 11:302–307

    Google Scholar 

  • Kelley KW (1989) Growth hormone, lymphocytes and macrophages. Biochem Pharmacol 38:705–713

    Google Scholar 

  • Keizer HA, Poortmans JR, Bunnik GS (1980) Influence of physical exercise on sex-hormone metabolism. J Appl Physiol 48:109–114

    Google Scholar 

  • Kindermann W, Schnabel A, Schmidt WM, Biro G, Cassens J, Weber F (1982) Catecholamine, growth hormone cortisol, insulin and sex hormones in anaerobic and aerobic exercise. Eur J Appl Physiol 49:389–399

    Google Scholar 

  • Kuoppasalmi K, Naveri H, Harkonen M, Aldercreutz A (1980) Plasma cortisol, androstenedione, testosterone, and luteinizing hormone in running exercise of different intensities. Scand J Clin Invest 40:403–409

    Google Scholar 

  • Lassare C, Girard F, Durand J, Raynaud J (1974) Kinetics of human growth hormone during submaximal exercise. J Appl Physiol 37:826–830

    Google Scholar 

  • Shephard RJ, Sidney KH (1975) Effects of physical exercise on plasma growth hormone and cortisol levels in human subjects. In: Willmore JH, Keogh JF (eds) Exercise and sport science reviews. Academic Press, New York, pp 1–30

    Google Scholar 

  • Sowers JR, Raj RR, Hershman JM, Carlson HE, McCalleum RW (1977) The effect of stressful diagnostic studies and surgery on anterior pituitary hormone release in man. Acta Endocrinol 86:25–32

    Google Scholar 

  • Sutton JR, Coleman MJ, Casey J, Lazarus L (1973) Androgen responses during physical exercise. BMJ:520–522

  • Sutton JR, Coleman MJ, Casey JH (1976a) Testosterone production rate during exercise. International Congress of Physical Activity Science (abstract) Quebec, p: 72. Cited in: {au{fnJurkowski} {gnJE}}, {au{fnJones} {gnNL}}, {au{fnWalker} {gnWC}}, {au{fnYounglai} {gnEV}}, {au{fnSutton} {gnJR}} ({dy1978}) {atOvarian hormonal responses to exercise}. {jtJ Appl Physiol} {vn44}:{pp109-114}

  • Sutton JR, Jones NL, Toews CJ (1976b) Growth hormone secretion in acid-base alterations at rest and during exercise. Clin Sci Mol Med 50:241–247

    Google Scholar 

  • Telford RD (1991) Endurance training. In: Pyke ITS (ed) Better coaching: advanced coaches manual. Australian Coaching Council, Canberra, pp 125–134

    Google Scholar 

  • Van Beaumont W (1972) Evaluation of haemoconcentration from haematocrit measurements. J Appl Physiol 32:712–713

    Google Scholar 

  • Viru A (1985) Hormones in muscular activity. CRC Press, Boca Raton

    Google Scholar 

  • Wilkerson JE, Horvath SM, Gutin B (1980) Plasma testosterone during treadmill exercise. J Appl Physiol 49:249–253

    Google Scholar 

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Gray, A.B., Telford, R.D. & Weidemann, M.J. Endocrine response to intense interval exercise. Europ. J. Appl. Physiol. 66, 366–371 (1993). https://doi.org/10.1007/BF00237784

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