Abstract
A cross-sectional case-control study was performed to identify some obstetric and gynaecologic factors that can influence spontaneous abortion. Statistical and epidemiologic analyses were done by multiple logistic regression to adjust OR through the β coefficient. A dicotomized outcome variable, representing spontaneous abortion, and different independent variables, representing distinct medical factors, were designed. The analysis was carried out with a personal computer and an appropriate statistic package.
The variables representing age over 35 and previous spontaneous abortions were shown to be risk factors, adjusted for the rest of variables. The variables representing parity and late menarcheal age lost significance when they were adjusted with multiple logistic regression.
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Calle M.E., Dominguez V. et al. (1989): Estilos de vida y su relación con el aborto espontáneo -Tokoginecologia Práctica 48: 455–457.
Casagrande I.T., Pike M.C. and Enderson (1982): Menarcheal age and spontaneous abortion: a causal connection? - Am. J. Epidemiol. 115: 481–483.
Coulan C.B. (1986): Pérdida recurrence inexplicable del embarazo - Clin. Obst. Ginecol. 4: 1253–1259 (Spanish edition).
Dand G., Czyglic F. and Mayaux M.J. (1980): Artificial insemination with frozen sperm: Protocol, method of analysis and results - Br. J. Obstet Gynaecol. 87: 1022.
Dominguez V., Calle M. et al. (1990): Abordaje epidemiológico del aborto espontáneo. Estudio de factores obstétricos y ginecológicos -Tokoginecologia Práctica 49: 265–270.
Hebert C.C., Bouyer J., Collin D. et al. (1986): Spontaneous abortion and interpregnancy interval -Eur. J. Obstet Gynecol. Reprod. Biol. 22: 125–132.
HWO - Serv. Inform. Tecnic. 1970; 461.
Javert C.T. (1957): Spontaneous and habitual abortion. McGrow-Hill Book Co. New York 100–124.
Levin A.A. (1984): Discontinued use of IUC device and pregnancy loss - Am. J. Obstet Gynecol. 7:149.
Liestol (1980): Menarcheal age and spontaneous abortion: a causal connection? - Am. J. Epidemiol. 111: 753–757.
Lubin J.H. (1981): A computer program for the analysis of matched case-control studies - Com. Biomed. Res. 14: 138–143.
McGee D.L. (1986): Epidemiologic programs for computer and calculators. A program for logistic regression on the IBM PC - Am. J. Epidemiol. 124: 702–705.
Miller J.F. and Williamson E. (1980): Fetal loss after implantation - Lancet 2: 554–556.
Mulcahy E. and Knaggss J.F. (1968): Effect of age, parity and cigarette smoking on outcome of pregnancy - Am. J. Obstet Gynecol. 101: 844–849.
Nelson Campos Filho, B.s., Franco E.L. MULTLR.A (1989): Microcomputer program for Multiple Logistic Regression by unconditional and conditional Maximum Likelihood methods - Am. J. Epidemiol. 129: 439–444
Poland B.J. (1982): Spontaneous abortion - Acta Obstet Ginecol. Scand. (Suppl.)102: 25.
Risch H.A. and Weiss N.S. (1988): Risk factors for spontaneous abortion and its recurrence - Am. J. Epidemiol. 128: 420–430.
Schlesselmann JJ (1982): Case-control studies: design, conduct, analysis - Oxford University press. New York, 206.
Shrisupan (1986): Caffeine consumption during pregnancy and association with late spontaneous abortion - Am. J. Obstet Gynecol. 154: 14–20.
Warburton D. and Fraser F.C. (1961): On probability that women who has spontaneous abortion will abort in subsequent pregnancies - Br. J. Obstet Gynaecol. 68: 784–789.
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Dominguez, V., Calls, E., Ortega, P. et al. Adjusting risk factors in spontaneous abortion by multiple logistic regression. Eur J Epidemiol 7, 171–174 (1991). https://doi.org/10.1007/BF00237362
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DOI: https://doi.org/10.1007/BF00237362