Abstract
The relationship between growth condition and production of cell-bound hemolysin by Proteus mirabilis 51959 strain was investigated. Hemolytic activity was not dependent on type of medium, oxygen accessibility and was inhibited in presence of N-ethylmaleimide, different sera or trypsine. Cell-free hemolysin was released to the medium during stationary-death phases of growth of fluid Proteus mirabilis and vulgaris cultures.
Similar content being viewed by others
References
Fry B.A. (1955): Glutamine synthesis by Microccus pyogenes var. aureus. - Biochem. J. 59: 579.585.
Hacker J. and Goebel W. (1987): Mechanism and methods for analysing pathogenecity. - Swiss. Biotech. 5: 21–31.
Koronakis V., Cross M., Senior B., Koronakis B. and Hughes C. (1987): The secreted hemolysins of Proteus mirabilis, Proteus vulgaris, and Morganella morgani are genetically related to each other and to the alphahemolysin of Escherichia coli. - J. Bacteriol. 169: 1509–1515.
Kotelko K., Kaca W., Róźalski A. and Deka M. (1983): Some biological features of Proteus bacilli. 2. Haemolytic activities of Proteus mirabilis and Proteus vulgaris strains. - Acta Microbiol. Polon. 4: 345–351.
Kreger BE, Craven D.E., Carling P.C. and Mc Cabe W.R. (1980): Gram negative bacteriemia. III. Reassessment of etiology, epidemiology and ecology in 612 patients. - Am. J. Med. 68: 332–334.
Mackman N., Nicaud J.M., Gray L. and Holland I.B. (1986): Secretion of haemolysin by Esherichia coli. -Curr. Top. Microbiol. Immunol. 125: 159–181.
Peerbooms P.G.H., Verweij A.M.J.J. and MacLaren D.M. (1983): Investigation of the haemolytic activity of Proteus mirabilis strains. - Antonie van Leeuwenhoek J. Microbiol. Serol. 49: 1–11.
Peerbooms P.G.H., Verweji A.M.J.J. and MacLaren D.M. (1984): Vero cell invasiveness of Proteus mirabilis. - Infect. Immun. 43: 1068–1071.
Peerbooms P.G.H., Verweji A.M.J.J. and MacLaren D.M. (1985): Uropathogenic properties of Proteus mirabilis and Proteus vulgaris. - J. Med. Microbiol. 19: 55–60.
Róźalski A., Dlugońska H. and Kotelko K. (1986): Cell invasiveness of Proteus mirabilis and Proteus vulgaris strains. - Archiv. Immun. Ther. Exp. 34: 505–512.
Róźalski A. and Kotelko K. (1987): Hemolytic activity and invasiveness in strains of Proteus penneri. - J. Clin. Microbiol. 25: 1094–1096.
Senior B.W. and Hughes C. (1987): Production and properties of haemolysins from clinical isolates of the Proteeae. - J. Med. Microbiol. 24: 17–25.
Smith H.W. (1963): The haemolysins of Escherichia coli. - J. Path. Bacteriol. 85: 197–211.
Swihart K.G. and Welch R.A. (1990): The HpmA hemolysin is more common than H1pyA among Proteus isolates. - Infect. Immun. 58: 1853–1860.
Welch R.A. (1987): Identification of two different hemolysin determinants in uropathogenic Proteus isolates. - Infec. Immun. 55: 2183–2190.
Author information
Authors and Affiliations
Additional information
Corresponding author.
Rights and permissions
About this article
Cite this article
Kaca, W., Ró\`zalski, A. Characterization of cell-bound and cell-free hemolytic activity of proteus strains. Eur J Epidemiol 7, 159–165 (1991). https://doi.org/10.1007/BF00237360
Issue Date:
DOI: https://doi.org/10.1007/BF00237360