Summary
Contralateral clicks normally activate units in the inferior colliculus of rats. Ipsilateral clicks usually inhibit this activity when their intensity just exceeds the contralateral intensity. When the contralateral dorsal and intermediate acoustic striae are lesioned as they pass over the restiform body, ipsilateral clicks inhibit even if they are substantially less intense than contralateral clicks. Contralateral click thresholds for unit activation are elevated by about 10 dB, but this shift in sensitivity cannot account for the marked advantage gained by the ipsilateral inhibitory input. These findings suggest that one or both of these pathways contributes heavily to binaural interaction at the inferior colliculus.
Similar content being viewed by others
References
Cajal, S.R.y: Histologie du systeme nerveux de l'homme et des vertebres (trans. L. Azoulay). Tome I. Madrid: Institute Ramón y Cajal 1909
Evans, E.F., Nelson, P.G.: The responses of single neurones in the cochlear nucleus of the cat as a function of their location and the anesthetic state. Exp. Brain Res. 17, 402–427 (1973a)
Evans, E.F., Nelson, P.G.: On the functional relationship between the dorsal and ventral divisions of the cochlear nucleus of the cat. Exp. Brain Res. 17, 428–442 (1973b)
Flammino, F., Clopton, B.M.: Neural responses in the inferior colliculus of albino rat to binaural stimuli. J. acoust. Soc. Amer. 57, 692–695 (1975)
Fernandez, C., Karapas, F.: The course and termination of the striae of Monakow and Held in the cat. J. comp. Neurol. 131, 371–386 (1967)
Galambos, R.: Suppression of auditory nerve activity by stimulation of efferent fibers to cochlea. J. Neurophysiol. 19, 424–437 (1956)
Godfrey, D.A., Kiang, N.Y.S., Norris, B.E.: Single unit activity in the posteroventral cochlear nucleus of the cat. J. comp. Neurol. 162, 247–268 (1976)
Goldberg, J.M., Brown, P.B.: Functional organization of the dog superior olivary complex: an anatomical and electrophysiological study. J. Neurophysiol. 31, 639–656 (1968)
Hall, J.L. II: Binaural interaction in the accessory superior-olivary nucleus of the cat. J. acoust. Soc. Amer. 37, 814–823 (1965)
Hall, J.G.: Hearing and primary auditory centres of the whales. Acta oto-laryng. (Stockh.) Suppl. 224, 244–250 (1967)
Hall, J.G., Lindeman, H.H., Mathisen, H.: The cochlea and the cochlear nuclei in the seals Crystrophora cristata and Phocida Groenlandica. Neurobiologia 4, 105–115 (1974)
Harrison, J.M., Warr, W.B.: A study of the cochlear nuclei and ascending auditory pathways of the medulla. J. comp. Neurol. 119, 341–379 (1962)
Irving, R., Harrison, J.M.: The superior olivary complex and audition: a comparative study. J. comp. Neurol. 130, 77–86 (1967)
Klinke, R., Boerger, G., Gruber, J.: The alteration of afferent, tone-evoked activity of neurons of the cochlear nucleus, following acoustic stimulation of the contralateral ear. J. acoust. Soc. Amer. 45, 788–789 (1969)
Mast, T.E.: Binaural interaction and contralateral inhibition in the dorsal cochlear nucleus of the chinchilla. J. Neurophysiol. 33, 108–115 (1970)
Mast, T.E.: Dorsal cochlear nucleus of the chinchilla: excitation by contralateral sound. Brain Res. 62, 61–70 (1973)
Osen, K.K.: Projection of the cochlear nuclei on the inferior colliculus in the cat. J. comp. Neurol. 144, 355–369 (1972)
Starr, A., Don, M.: Responses of squirrel monkey medial geniculate units to binaural click stimuli. J. Neurophysiol. 35, 501–517 (1972)
Warr, W.B.: Fiber degeneration following lesions in the posteroventral cochlear nucleus of the cat. Exp. Neurol. 23, 140–155 (1969)
Author information
Authors and Affiliations
Additional information
This work was partially supported by NIH Grant No. NS-13052.
Rights and permissions
About this article
Cite this article
Bengry, M.F., Silverman, M.S. & Clopton, B.M. Effects of lesioning the dorsal and intermediate acoustic striae on binaural interaction at the inferior colliculus. Exp Brain Res 28, 211–219 (1977). https://doi.org/10.1007/BF00237097
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00237097