Summary
Visual receptive fields of 42 LGN cells from normal cats and 110 cells from striped cylinder-reared kittens were studied with the aid of a computer controlled optical system. In the normal cats, ten of the 42 cells were weakly biased for orientation of the visual stimulus when tested with bars swept through the receptive field. Of those ten, eight were classified as transient. The orientation preferences of the ten biased units appeared randomly distributed around the clock.
Of the LGN cells from the cylinder-reared group, about half of the transient cells had weak biases for orientation; only 7% of the sustained cells had biases. The orientation preferences of the biased LGN cells in the stripe-reared animals were either parallel to or orthogonal to the stripes each animal saw during its time in the conditioning cylinder.
In 16 out of 18 of the biased LGN cells it was found that increasing the velocity of the test target reduced or eliminated the bias apparent at the lower velocity. For some LGN cells special techniques, such as inhibition of activated discharge, were needed to reveal orientation biases. The results described here, considered with data from others, suggest a role for the corticofugal projection in modulating the responses of some LGN cells.
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Bishop, P.O., Coombs, J.S., Henry, G.H.: Receptive fields of simple cells in the cat striate cortex. J. Physiol. (Lond.) 231, 31–60 (1973)
Blasdel, G.G., Mitchell, D.E., Muir, D.W., Pettigrew, J.D.: A physiological and behavioral study in cats of the effect of early visual experience with contours of a single orientation. J. Physiol. (Lond.) 265, 615–636 (1977)
Blakemore, C.: Developmental factors in the formation of feature extracting neurons. In: The Neurosciences, Third Study Program (eds. F.O. Schmitt and F.G. Worden). Cambridge, Mass.: MIT Press 1973
Blakemore, C., Cooper, G.F.: Development of the brain depends on visual environment. Nature (Lond.) 241, 467–468 (1970)
Blakemore, C., Mitchell, D.M.: Environmental modification of the visual cortex and the neural basis of learning and memory. Nature (Lond.) 241, 467–468 (1973)
Cleland, B.G., Dubin, M.W., Levick, W.R.: Simultaneous recording of input and output of lateral geniculate neurons. Nature New Biol. 231, 191–192 (1971a)
Cleland, B.G., Dubin, M.W., Levick, W.R.: Sustained and transient neurons in the cat's lateral geniculate nucleus. J. Physiol. (Lond.) 217, 473–496 (1971b)
Creutzfeldt, O.D., Heggelund, P.: Neural plasticity in visual cortex of adult cats after exposure to visual patterns. Science 188, 1025–1027 (1975)
Dreher, B., Sanderson, K.J.: Receptive field analysis: Responses to moving visual contours by single lateral geniculate neurons in the cat. J. Physiol. (Lond.) 234, 95–118 (1973)
Enroth-Cugell, C., Robson, J.G.: The contrast sensitivity of retinal ganglion cells of the cat. J. Physiol. (Lond.) 187, 517–552 (1966)
Freund, H.-J.: Neuronal mechanisms of the lateral geniculate body. In: Handbook of Sensory Physiology. Vol. VII/3 (ed. R. Jung). Berlin-Heidelberg-New York: Springer 1973
Garey, L.J., Jones, E.G., Powell, T.P.S.: Interrelationships of striate and extrastriate cortex with primary relay sites of the visual pathways. J. Neurol. Neurosurg. Psychiat. 131, 135–157 (1968)
Gilbert, C.D., Kelly, J.P.: The projections of cells in different layers of the cat's visual cortex. J. comp. Neurol. 163, 81–106 (1975)
Guillery, R.W.: Patterns of fiber degeneration in the dorsal lateral geniculate nucleus of the cat following lesions in the visual cortex. J. comp. Neurol. 130, 197–222 (1967)
Hammond, P.: Cat retinal ganglion cells: size and shape of receptive field centers. J. Physiol. (Lond.) 242, 99–118 (1974)
Hirsch, H.V.B., Spinelli, D.N.: Visual experience modifies distribution of horizontally and vertically oriented receptive fields in cats. Science 168, 869–871 (1970)
Huffman, K. -P., Stone, J., Sherman, S.M.: Relay of receptive field properties in dorsal lateral geniculate nucleus of the cat. J. Neurophysiol. 35, 518–531 (1972)
Holländer, H.: The projection from the visual cortex to the lateral geniculate body (LGB), an experimental study with silver impregnation methods in the cat. Exp. Brain Res. 10, 219–235 (1970)
Hubel, D.H., Wiesel, T.N.: Receptive fields, binocular interaction and functional architecture in the cat's visual cortex. J. Physiol. (Lond.) 160, 106–154 (1962)
Hubel, D.H., Wiesel, T.N.: A re-examination of stereoscopic mechanisms in area 17 of the cat. J. Physiol. (Lond.) 232, 29P-30P (1973)
Kalil, R.E., Chase, R.: Corticofugal influence on activity of lateral geniculate neurons in the cat. J. Neurophysiol. 33, 459–474 (1970)
Kawamura, S., Sprague, J.M., Niimi, K.: Corticofugal projections from the visual cortices to the thalamus, pretectum and superior colliculus in the cat. J. comp. Neurol. 158, 339–362 (1974)
Leventhal, A.G., Hirsch, H.V.B.: Cortical effect of early selective exposure to diagonal lines. Science 190, 902–904 (1975)
Levick, W.R.: Another tungsten microelectrode. Med. biol. Engng. 10, 510–515 (1972)
Movshon, J.A.: The velocity tuning of single units in cat striate cortex. J. Physiol. (Lond.) 249, 445–468 (1975)
Niimi, K., Kawamura, S., Ishimaru, S.: Projections of the visual cortex to the lateral geniculate and posterior thalamic nuclei in the cat. J. comp. Neurol. 143, 279–312 (1971)
Nikara, T., Bishop, P.O., Pettigrew, J.D.: Analysis of retinal correspondence by studying receptive fields of binocular single units in cat striate cortex. Exp. Brain Res. 6, 353–372 (1968)
Pettigrew, J.D.: The effect of visual experience on the development of stimulus specificity by kitten cortical neurones. J. Physiol. (Lond.) 237, 49–74 (1974)
Pettigrew, J.D., Nikara, T., Bishop, P.O.: Responses to moving slits by single units in cat striate cortex. Exp. Brain Res. 6, 373–390 (1968)
Sanderson, K.J.: The projection of the visual field to the lateral geniculate and medial interlaminar nuclei in the cat. J. comp. Neurol. 143, 101–118 (1971)
Sanderson, K.J., Bishop, P.O., Darian-Smith, I.: The properties of the binocular receptive fields of lateral geniculate neurons. Exp. Brain Res. 13, 178–207 (1971)
Sanderson, K.J., Darian-Smith, I., Bishop, P.O.: Binocular corresponding receptive fields of single units in the cat dorsal lateral geniculate nucleus. Vision Res. 9, 1297–1310 (1969)
Schmielau, F., Singer, W.: Corticofugal control of the cat lateral geniculate nucleus. Exp. Brain Res. 13, 363 (1975)
Sherman, S.M., Hoffman, K.-P., Stone, J.: Loss of a specific cell type from dorsal LGN of visually deprived cats. J. Neurophysiol. 35, 532–541 (1972)
Stone, J., Fukuda, Y.: Properties of cat retinal ganglion cells: A comparison of W-cells with X- and Y-cells. J. Neurophysiol. 37, 722–748 (1974)
Stryker, M.P., Sherk, H.: Modification of cortical orientation selectivity in the cat by restricted visual experience: A reexamination. Science 190, 904–906 (1975)
Tömböl, T., Hajdu, F., Somogyi, Gy.: Identification of the Golgi picture of the layer VI cortico-geniculate projection neurons. Exp. Brain Res. 24, 107–110 (1975)
Updyke, B.V.: The patterns of projection of cortical areas 17, 18 and 19 onto the laminae of the dorsal lateral geniculate nucleus in the cat. J. comp. Neurol. 163, 377–396 (1975)
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Daniels, J.D., Norman, J.L. & Pettigrew, J.D. Biases for oriented moving bars in lateral geniculate nucleus neurons of normal and stripe-reared cats. Exp Brain Res 29, 155–172 (1977). https://doi.org/10.1007/BF00237039
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DOI: https://doi.org/10.1007/BF00237039