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Full thickness, split thickness and culture epithelium as a treatment for ulcerative lichen planus

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Summary

Ulcerative lichen planus is a rare and chronic form of lichen planus. The disease affects mainly the feet and the oral cavity. This form is not only extremely painful and disabling, but carries the hazards of malignant transformation. Only nine patients described in the literature had excision and skin grafting of their lesions, with good short and long-term results. We present a case report of a patient with 27 years history of ulcerative lichen planus and multiple skin grafting and recurrencies. We present an alternative method of treatment with culture epithelium allograft as a temporary measure.

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References

  1. Altmann J, Perry HO (1961) The variations and course of lichen planus. Arch Dermatol 84: 179

    Google Scholar 

  2. Black MM, Wilson-Jones E (1972) The role of epidermis in the histopathogenesis of lichen planus. Arch Dermatol 105: 81

    Google Scholar 

  3. Burt A, Pallet CD, Sloane JP, O'Hara MJ, Schafler KF, Yardeni P, Eldad A, Clarke JA, Gusterson B (1989) Survival of cultured allografts in patients with burns assessed with probe specific to Y-chromosome. Br Med J 298: 915–917

    Google Scholar 

  4. Carter DM, Lin AN, Varghese MC, Caldwell D, Pratt LA, Eisinger M (1987) Treatment of junctional epidermolysis bullosa with epidermal autografts. J Am Acad Dermatol 17: 246–250

    Google Scholar 

  5. Crotty CP, Daniel SUWP, Winkelmann RK (1980) Ulcerative lichen planus. Arch Dermatol 116: 1252

    Google Scholar 

  6. Domonkos AN, Arnold HL, Odom RB (1982) Andrews diseases of the skin. Clinical dermatology, 7th edn. Saunders, New York

    Google Scholar 

  7. Green H, Kehinde O, Thomas J (1979) Growth of culture epidermis cells into multiple epidermal cells grafts suitable for grafting. Proc Natl Acad Sci USA 76: 5665

    Google Scholar 

  8. Hefton JM, Madden MR, Finkelstein JL (1983) Grafting of burns patients with allografts of cultured epidermal cells. Lancet II: 428

    Google Scholar 

  9. Koberg W, Shettler D, Selle G (1965) Development of carcinoma as sequel of lichen ruber planus. Münch Med Wochenschr 107: 463

    Google Scholar 

  10. Leigh I, Purkis PE, Navsaria HA, Phillips TJ (1987) Treatment of chronic venous ulcers with cultured of allogenic keratinocytes. Br J Dermatol 117: 591–597

    Google Scholar 

  11. Phillips TJ, Kehinde O, Green H, Gilchrist B (1989) Treatment of skin ulcers with cultured epidermal allografts. Symposium on Cultured Epithelium Grafts in Wound Closure, New Orleans, LA

  12. Pinkus H, Mehregan AH (1969) A guide to dermatohistopathology. Butterworths, London

    Google Scholar 

  13. Sabouraud R (1910) Quelques points d'anatomie pathologique de lichen plan de Wilson. Ann Dermatol 1: 491

    Google Scholar 

  14. Samman PD (1961) Lichen planus — an analysis of 200 cases. Trans St Johns Hosp Dermatol Soc 46: 36

    Google Scholar 

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Eldad, A., Burt, A. & Clarke, J.A. Full thickness, split thickness and culture epithelium as a treatment for ulcerative lichen planus. Eur J Plast Surg 13, 173–175 (1990). https://doi.org/10.1007/BF00236373

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