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Effects of heat acclimation on the secretory products of the submaxillary gland of the rat

An ultrastructural and biochemical study

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Summary

Secretory granule area and glycoprotein concentration of the saliva in the submaxillary gland of rats were measured during various stages of acclimation to heat at 34±1° C. Granule size decreased by 18% during the first five days of heat acclimation (0.025<p<0.05) after which period it increased to reach 118% of the control levels after 28 days (p<0.05). Glycoprotein concentration in the saliva of stimulated glands rose above control levels, reaching a maximum between the 2nd and 5th day of acclimation (p<0.05). It was concluded that the initial decrease in granule size reflects a decrease in glycoprotein content following an increase in salivary flow known to occur at high ambient temperatures. The subsequent increase in granule size is considered an adaptation of the gland to continuous stimulation. The rise in salivary glycoprotein concentration suggests increased efficiency of the secretory mechanism.

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Authors and Affiliations

  1. Division of Oral Pathology, Hebrew University-Hadassah School of Dental Medicine, Israel

    W. A. Soskolne &  Michal Horowitz

  2. Dept. of Physiology, Hebrew University-Hadassah Schools of Medicine and Dental Medicine, Jerusalem, Israel

    W. A. Soskolne &  Michal Horowitz

Authors
  1. W. A. Soskolne
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  2. Michal Horowitz
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Supported by the joint research fund of the Hebrew University-Hadassah School of Dental Medicine founded by the Alfa Omega Fraternity and the Hadassah Medical Organization

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Soskolne, W.A., Horowitz, M. Effects of heat acclimation on the secretory products of the submaxillary gland of the rat. Cell Tissue Res. 196, 147–151 (1979). https://doi.org/10.1007/BF00236355

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  • DOI: https://doi.org/10.1007/BF00236355

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