Skip to main content
SpringerLink
Log in

Chronic ‘blindness’ following lesions of nonvisual cortex in the monkey

  • Regular Papers
  • Published:
Experimental Brain Research Aims and scope Submit manuscript

Summary

Chronic ‘blindness’ was produced in monkeys by a lesion that combined right optic tract section, forebrain commissurotomy, and a large cortical ablation in the left hemisphere that spared most of the modality specific visual cortex. The finding suggests that, contrary to implications from earlier studies, central visual processes can influence behavior only with the participation of nonvisual cortex.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Brinkman J, Kuypers HGJM (1972) Splitbrain monkeys: cerebral control of ipsilateral and contralateral arm, hand, and finger movements. Science 176: 536–539

    CAS  PubMed  Google Scholar 

  • Denny-Brown D, Chambers RA (1958) The parietal lobe and behavior. Res Publ Ass Res Nerv Ment Dis 36: 35–117

    Google Scholar 

  • Doty RW (1983) Nongeniculate afferents to striate cortex in macaques. J Comp Neurol 218: 159–173

    Google Scholar 

  • Ettlinger G, Kalsbeck JE (1962) Changes in tactile discrimination and in visual reaching after successive and simultaneous bilateral posterior parietal ablations in the monkey. J Neurol Neurosurg Psychiat 25: 6–268

    Google Scholar 

  • Galambos R, Norton TT, Frommer GP (1967) Optic tract lesions sparing pattern vision in cats. Exp Neurol 18: 8–25

    Google Scholar 

  • Gazzaniga MS (1966) Visuomotor integration in split-brain monkeys with other cerebral lesions. Exp Neurol 16: 289–298

    Google Scholar 

  • Haaxma R, Kuypers HGJM (1975) Intrahemispheric cortical connexions and visual guidance of hand and finger movements in the rhesus monkey. Brain 98: 239–260

    Google Scholar 

  • Jones EG, Powell TPS (1970) An anatomical study of converging sensory pathways within the cerebral cortex of the monkey. Brain 93: 793–820

    CAS  PubMed  Google Scholar 

  • Keating EG (1975) Effects of prestriate and striate lesions on the monkeys ability to locate and discriminate visual forms. Exp Neurol 47: 16–25

    Google Scholar 

  • Keating EG (1977) Cortical blindness in the monkey after overlapping lesions of the striate cortex and retinal photoreceptors: a further limit to redundancy in the topography of the visual system. Exp Neurol 55: 234–246

    Google Scholar 

  • Kuypers HGJM, Szwarcbart MK, Mishkin M, Rosvold HE (1965) Occipitotemporal corticocortical connections in the rhesus monkey. Exp Neurol 11: 245–262

    Google Scholar 

  • Mishkin M (1966) Visual mechanisms beyond striate cortex. In: Russell RW (ed) Frontiers in physiological psychology. Academic Press, New York

    Google Scholar 

  • Myers RE, Sperry RW, McCurdy NW (1962) Neural mechanisms in visual guidance of limb movement. Arch Neurol 7: 195–202

    Google Scholar 

  • Nakamura RK, Mishkin M (1979) Chronic blindness following nonvisual cortical lesions in monkeys. Neurosci Abst 5: 800

    Google Scholar 

  • Nakamura RK, Mishkin M (1980) Blindness in monkeys following non-visual cortical lesions. Brain Res 188: 572–577

    Google Scholar 

  • Nakamura RK, Mishkin M (1982) Chronic blindness following nonvisual lesions in monkeys: partial lesions and disconnection effects. Neurosci Abst 8: 812

    Google Scholar 

  • Olszewski J (1952) The thalamus of the Macaca mulatta. S Karger Basel

    Google Scholar 

  • Pandya DN, Kuypers HGJM (1969) Cortico-cortical connections in the rhesus monkey. Brain Res 13: 13–36

    Google Scholar 

  • Pasik T, Pasik P (1980) Extrageniculate vision in primates. In: Lessell, ST, Vandalen JTW (eds) Neuro-ophthalmology, Vol 1. A series of critical surveys of the international literature. Excerpta Medica, Amsterdam

    Google Scholar 

  • Pribram KH, Spinelli DN, Reitz SL (1969) The effects of radical disconnexion of occipital and temporal cortex on visual behaviour of monkeys. Brain 92: 301–312

    Google Scholar 

  • Sperry RW, Myers RE, Schrier AM (1960) Perceptual capacity of the isolated visual cortex in the cat. Q J Exp Psychol 12: 65–71

    Google Scholar 

  • Tigges J, Tigges M, Cross NA, McBride RL, Letbetter WD, Anschel S (1982) Subcortical structures projecting to visual cortical areas in squirrel monkey. J Comp Neurol 209: 29–40

    Google Scholar 

  • Tigges J, Walker LC, Tigges M (1983) Subcortical projections to the occipital and parietal lobes of the chimpanzee brain. J Comp Neurol 220: 106–115

    Google Scholar 

  • Ungerleider LG, Mishkin M (1982) Two cortical visual systems. In: Ingle DJ, Goodale MA, Mansfield RJW (eds) Analysis of visual behavior. The MIT Press, Cambridge MA

    Google Scholar 

  • Weiskrantz L (1978) Some aspects of visual capacity in monkeys and man following striate cortex lesions. Arch Ital Biol 116: 318–323

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Institute of Mental Health, Building 9 Room 1N107, 20892, Bethesda, MD, USA

    R. K. Nakamura & M. Mishkin

Authors
  1. R. K. Nakamura
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Mishkin
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nakamura, R.K., Mishkin, M. Chronic ‘blindness’ following lesions of nonvisual cortex in the monkey. Exp Brain Res 63, 173–184 (1986). https://doi.org/10.1007/BF00235661

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00235661

Key words

Search

Navigation