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Labyrinthine influence on cat forelimb motoneurons

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Summary

  1. 1.

    Intracellular responses in forelimb motoneurons to electrical stimulation of the whole labyrinth and of individual semicircular canal nerves were studied in decerebrated, unanesthetized cats.

  2. 2.

    Stimulation of the whole labyrinth typically produced EPSPs, usually bilaterally, in forelimb extensor (LON, LAT, MED) and shoulder (SI) motoneurons and bilateral IPSPs in forelimb flexor (BIC) motoneurons.

  3. 3.

    Latencies of PSPs indicated that most of those in extensor motoneurons were trisynaptic and many seen in flexor motoneurons may involve four synapses.

  4. 4.

    In the cells sampled, stimulation of the anterior, horizontal or posterior canal nerves often evoked EPSPs in extensor and IPSPs in flexor motoneurons, both ipsi-and contralaterally. Responses to canal stimulation were weaker and more variable than those to stimulation of the whole nerve.

  5. 5.

    Transection of the MLF in the lower medulla had no effect on PSPs evoked in forelimb motoneurons. Lesions in the medulla in the area of the LVST greatly reduced the occurrence of contralateral EPSPs in extensor and IPSPs in flexor motoneurons. The pathway linking labyrinths to forelimb motoneurons therefore appears to include the LVST. Hemisection shows that the pathway to contralateral motoneurons descends in the cord on the side of the stimulated labyrinth before crossing to influence these cells.

  6. 6.

    Labyrinthine control of forelimb motoneurons is less direct than control of neck and back motoneurons. It is suggested that the interneuron in the pathway to forelimb motoneurons is the site of integration of labyrinthine with other reflexes.

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References

  • Akaike, T., Fanardjian, V.V., Ito, M., Ohno, T.: Electrophysiological analysis of the vestibulo spinal reflex pathway of rabbit. II. Synaptic actions upon spinal neurons. Exp. Brain Res. 17, 497–515 (1973)

    Google Scholar 

  • Aoyama, M., Hongo, T., Kudo, N., Tanaka, R.: Convergent effects from bilateral vestibulospinal tracts on spinal interneurons. Brain Res. 35, 250–253 (1971)

    Google Scholar 

  • Batini, C., Moruzzi, G., Pompeiano, O.: Cerebellar release phenomena. Arch. ital. Biol. 95, 71–95 (1957)

    Google Scholar 

  • Berthoz, A., Anderson, J.H.: Frequency analysis of vestibular influence on extensor motoneu rons. I. Response to tilt in forelimb extensors. Brain Res. 34, 370–375 (1971)

    Google Scholar 

  • Bruggencate, G. ten, Lundberg, A.: Facilitatory interaction in transmission to motoneurones from vestibulospinal fibres and contralateral primary afferents. Exp. Brain Res. 19, 248–270 (1974)

    Google Scholar 

  • Cohen, B., Suzuki, J.-I., Bender, M.B.: Eye movements from semicircular canal nerve stimulation in the cat. Ann. Otol. (St. Louis) 73, 153–169 (1964)

    Google Scholar 

  • Duensing, F., Schaefer, K.P.: Über die Konvergenz verschiedener labyrinthärer Afferenzen auf einzelne Neurone des Vestibulariskerngebietes. Arch. Psychiat. Nervenkr. 199, 345–371 (1959)

    Google Scholar 

  • Eccles, J.C.: The Physiology of Synapses. Berlin-Göttingen-Heidelberg-New York: Springer 1964

    Google Scholar 

  • Eccles, J.C., Eccles, R.M., Lundberg, A.: The convergence of monosynaptic excitatory afferents on to many different species of alpha motoneurones. J. Physiol. (Lond.) 137, 22–50 (1957)

    Google Scholar 

  • Flock, Å.: Structure of the macula utriculi with special reference to directional interplay of sensory responses as revealed by morphological polarization. J. Cell Biol. 22, 413–431 (1964)

    Google Scholar 

  • Gernandt, B.E., Ades, H.W.: Spinal motor responses to acoustic stimulation. Exp. Neurol. 10, 52–66 (1964)

    Google Scholar 

  • Gernandt, B.E., Gilman, S.: Descending vestibular activity and its modulation by proprio ceptive, cerebellar and reticular influences. Exp. Neurol. 1, 274–304 (1959)

    Google Scholar 

  • Grillner, S., Hongo, T., Lund, S.: The vestibulospinal tract. Effects on alpha motoneurons in the lumbosacral spinal cord in the cat. Exp. Brain Res. 10, 94–120 (1970)

    Google Scholar 

  • Hongo, T., Kudo, N., Tanaka, R.: Effects from the vestibulospinal tract on the contralateral hindlimb motoneurones in the cat. Brain Res. 31, 220–223 (1971)

    Google Scholar 

  • de Kleijn, A., Magnus, R.: Über die Funktion der Otolithen. I. Mitteilung. Otolithenstand bei den tonischen Labyrinthreflexen. Pflügers Arch. ges. Physiol. 186, 6–38 (1921)

    Google Scholar 

  • Klüver, H., Barrera, E.: A method for the combined staining of cells and fibers in the nervous system. J. Neuropath. exp. Neurol. 12, 400–403 (1953)

    Google Scholar 

  • Lindeman, H.H.: Studies on the morphology of the sensory regions of the vestibular appara tus. Ergebn. Anat. 42, 7–110 (1969)

    Google Scholar 

  • Lund, S., Pompeiano, O.: Monosynaptic excitation of alpha motoneurones from supraspinal structures in the cat. Acta physiol. scand. 73, 1–21 (1968)

    Google Scholar 

  • Magherini, P.C., Precht, W., Richter, A.: Vestibulospinal effects on hindlimb motoneurons of the frog. Pflügers Arch. 348, 211–223 (1974)

    Google Scholar 

  • Magnus, R.: Some results of studies in the physiology of posture. Lancet 211, 531–536, 585–588 (1926)

    Google Scholar 

  • Maunz, R.A., Maeda, M., Wilson, V.J.: Labyrinthine control of cat forelimb motoneurons. 4th Ann. Meeting Soc. Neurosci. 328 (1974)

  • Peterson, B.W.: Distribution of neural responses to tilting within vestibular nuclei of the cat. J. Neurophysiol. 33, 750–767 (1970)

    Google Scholar 

  • Peterson, B.W., Felpel, L.P.: Excitation and inhibition of reticulospinal neurons by vestibular, cortical and cutaneous stimulation. Brain Res. 27, 373–376 (1971)

    Google Scholar 

  • Petras, J.M.: Cortical, tectal and tegmental fiber connections in the spinal cord of the cat. Brain Res. 6, 275–324 (1967)

    Google Scholar 

  • Rall, W., Burke, R.E., Smith, T.G., Nelson, P.G., Frank, K.: Dendritic location of synapses and possible mechanisms for the monosynaptic EPSP in motoneurons. J. Neurophysiol. 30, 1169–1193 (1967)

    Google Scholar 

  • Reighard, J., Jennings, H.S.: Anatomy of the cat (3d ed.). New York: Holt 1935

    Google Scholar 

  • Reinoso-Suarez, F.: Topographischer Hirnatlas der Katze. Darmstadt: Merck 1961

    Google Scholar 

  • Roberts, T.D.M.: Neurophysiology of Postural Mechanisms. London: Butterworths 1967

    Google Scholar 

  • Roberts, T.D.M.: Changes in stretch reflexes in limb extensor muscles during position reflexes from the labyrinth in the cat. J. Physiol. (Lond.) 211, 45P (1970)

  • Rosenberg, J.R., Lindsay, K.W.: Asymmetric tonic labyrinthine reflexes. Brain Res. 63, 347–350 (1973)

    Google Scholar 

  • Sherrington, C.S.: Flexion-reflex of the limb, crossed extension-reflex, and reflex stepping and standing. J. Physiol. (Lond.) 40, 28–121 (1910)

    Google Scholar 

  • Shimazu, H., Precht, W.: Tonic and kinetic responses of cat's vestibular neurons to horizontal angular acceleration. J. Neurophysiol. 28, 991–1013 (1965)

    Google Scholar 

  • Sterling, P., Kuypers, H.G.J.M.: Anatomical organization of the brachial spinal cord of the cat. III. The propriospinal connections. Brain Res. 7, 419–443 (1968)

    Google Scholar 

  • Suzuki, J.-I., Cohen, B.: Head, eye, body and limb movements from semicircular canal nerves. Exp. Neurol. 10, 393–405 (1964)

    Google Scholar 

  • Suzuki, J.-I., Goto, K., Tokumasu, K., Cohen, B.: Implantation of electrodes near individual vestibular nerve branches in mammals. Ann. Otol. (St. Louis) 78, 815–826 (1969)

    Google Scholar 

  • Szentágothai, J.: Die Rolle der Einzelnen Labyrinthrezeptoren bei der Orientation von Augen und Kopf im Raume. Budapest: Akademiai Kiado 1952

    Google Scholar 

  • Wilson, V.J.: Physiological pathways through the vestibular nuclei. Int. Rev. Neurobiol. 15, 27–81 (1972)

    Google Scholar 

  • Wilson, V.J., Felpel, L.P.: Specificity of semicircular canal input to neurons in the pigeon vestibular nuclei. J. Neurophysiol. 35, 253–264 (1972)

    Google Scholar 

  • Wilson, V.J., Kato, M., Peterson, B.W., Wylie, R.M.: A single-unit analysis of the organiza tion of Deiters' nucleus. J. Neurophysiol. 30, 603–619 (1967)

    Google Scholar 

  • Wilson, V.J., Maeda, M.: Connections between semicircular canals and neck motoneurons in the cat. J. Neurophysiol. 37, 346–357 (1974)

    Google Scholar 

  • Wilson, V.J., Wylie, R.M., Marco, L.A.: Synaptic inputs to cells in the medial vestibular nucleus. J. Neurophysiol. 31, 176–186 (1968)

    Google Scholar 

  • Wilson, V.J., Yoshida, M.: Comparison of effects of stimulation of Deiters' nucleus and medial longitudinal fasciculus on neck, forelimb, and hindlimb motoneurons. J. Neurophysiol. 32, 743–758 (1969a)

    Google Scholar 

  • Wilson, V.J., Yoshida, M.: Monosynaptic inhibition of neck motoneurons by the medial vestibular nucleus. Exp. Brain Res. 9, 365–380 (1969b)

    Google Scholar 

  • Wilson, V.J., Yoshida, M., Schor, R.H.: Supraspinal monosynaptic excitation and inhibition of thoracic back motoneurons. Exp. Brain Res. 11, 282–295 (1970)

    Google Scholar 

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Authors and Affiliations

  1. The Rockefeller University, New York, USA

    M. Maeda, R. A. Maunz & V. J. Wilson

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  1. M. Maeda
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  2. R. A. Maunz
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  3. V. J. Wilson
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Supported in part by N.I.H. grants NS 02619 and NS 05463.

Recipient of N.I.H. Fellowship 1 F02 NS 55199.

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Maeda, M., Maunz, R.A. & Wilson, V.J. Labyrinthine influence on cat forelimb motoneurons. Exp Brain Res 22, 69–86 (1975). https://doi.org/10.1007/BF00235412

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  • DOI: https://doi.org/10.1007/BF00235412

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