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The temporal evolution of the distribution of dendritic spines in the visual cortex of normal and dark raised mice

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Summary

A set of equations which define the distribution of spines along the apical dendrites have been developed. They are satisfied by the distribution of spines and its evolution with the age in the apicals of the layer V pyramidal cells of the visual cortex in normal and dark raised mice. The principal equation describes the distribution of the spines with three coefficients IF, B and K whose values have a functional relation with the age T of the animal. This relation has been defined by three additional equations whose coefficients were calculated. The equations have been used to predict the distribution of dendritic spines corresponding to age-groups of mice not previously studied and to find out the age of mice from the data of their known spine distribution resolving the inverse equations of IF (T) and B(T).

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Ruiz-Marcos, A., Valverde, P. The temporal evolution of the distribution of dendritic spines in the visual cortex of normal and dark raised mice. Exp Brain Res 8, 284–294 (1969). https://doi.org/10.1007/BF00234254

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