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Production of canthin-6-one alkaloids by cell suspension cultures of Brucea javanica (L.) Merr.

Plant Cell Reports volume 9, pages 261–263 (1990)Cite this article

Abstract

Cell suspension cultures of Brucea javanica (L.) Merr. were used to determine culture growth characteristics and production of canthin-6-one alkaloids. The major alkaloids produced were canthin-6-one, 11-hydroxycanthin-6-one, 5-methoxycanthin-6-one and 11-methoxycanthin-6-one. Alkaloids were synthesised throughout the 36 day growth cycle of the cells with maximum amounts within the cells occurring between days 20 to 28; approximately 10% of the alkaloids were in the medium at day 24 rising to 45% at day 32.

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Author notes

  1. Karin C. -S. Liu

    Present address: School of Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China

Affiliations

  1. Department of Pharmacognosy, The School of Pharmacy, University of London, 29-39 Brunswick Square, WC1N 1AX, London, UK

    Karin C. -S. Liu, Shi-Lin Yang, Margaret F. Roberts & J. David Phillipson

Authors
  1. Karin C. -S. Liu
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  2. Shi-Lin Yang
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  3. Margaret F. Roberts
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  4. J. David Phillipson
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Communicated by M. H. Zenk

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Liu, K.C.S., Yang, SL., Roberts, M.F. et al. Production of canthin-6-one alkaloids by cell suspension cultures of Brucea javanica (L.) Merr.. Plant Cell Reports 9, 261–263 (1990). https://doi.org/10.1007/BF00232297

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  • DOI: https://doi.org/10.1007/BF00232297

Keywords

  • Cell Suspension
  • Alkaloid
  • Suspension Culture
  • Maximum Amount
  • Growth Characteristic