Skip to main content
Log in

Fluorescence histochemical study on regional differences in the sympathetic nerve supply of the choroid plexus from various laboratory animals

  • Published:
Cell and Tissue Research Aims and scope Submit manuscript

Summary

The adrenergic nerve supply of the choroid plexus in all four ventricles was studied by the Falck-Hillarp histofluorescence technique in nine different species, and the noradrenaline concentration in whole plexus tissue was determined by a radioenzymatic method. The nerve density was usually in the order: third > lateral > fourth ventricular plexuses. Plexuses of the pig and cat possessed the largest number of nerves; the innervation was intermediary in the baboon, guinea-pig, rat, rabbit and hamster, whereas only few fluorescent nerves were found in the cow and mouse plexuses. Sympathetic denervation showed an ipsilateral supply from the superior cervical ganglia to the lateral plexuses and a mixed contribution to the midline plexuses. The total noradrenaline concentration varied between 0.10 and 0.73 ng per mg protein.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Björklund, A., Falck, B., Owman, Ch.: Fluorescence microscopic and microspectrofluorometric techniques for the cellular localization and characterization of biogenic amines. In: Methods of Investigative and Diagnostic Endocrinology (S.A, Berson, ed), Vol.1 The thyroid and biogenic amines (J.E. Rall and I.J. Kopin, eds.), pp. 318–368. Amsterdam: North Holland Publ. Comp. 1972

    Google Scholar 

  • Coyle, J.T., Henry, D.: Catecholamines in fetal and newborn rat brain. J. Neurochem. 21, 61–67 (1973)

    Google Scholar 

  • Cuello, A.C., Hiley, R., Iversen, L.L.: Use of catechol-O-methyl transferase for the enzyme radiochemical assay of dopamine. J. Neurochem. 21, 1337–1340 (1973)

    Google Scholar 

  • Edvinsson, L., Owman, Ch., Rosengren, E., West, K.A.: Concentration of noradrenaline in pial vessels, choroid plexus, and iris during two weeks after sympathetic ganglionectomy or decentralization. Acta Physiol. Scand. 85, 201–206 (1972)

    Google Scholar 

  • Edvinsson, L., Nielsen, K.C., Owman, Ch.: Cholinergic innervation of choroid plexus in rabbits and cats. Brain Res. 63, 500–503 (1973)

    Google Scholar 

  • Edvinsson, L., Nielsen, K.C., Owman, Ch., West, K.A.: Adrenergic innervation of the mammalian choroid plexus. Amer. J. Anat. 139, 299–308 (1974)

    Google Scholar 

  • Edvinsson, L., Håkanson, R., Lindvall, M., Owman, Ch., Svensson, K.-G.: Ultrastructural and biochemical evidence for a sympathetic neural influence on the choroid plexus. Exp. Neurol. 48, 241–251 (1975)

    Google Scholar 

  • Lindvall, M., Owman, Ch.: Early development of noradrenaline-containing sympathetic nerves in the choroid plexus system of the rabbit. Cell Tissue Res. 192, 195–203 (1978)

    Google Scholar 

  • Lindvall, M., Edvinsson, L., Owman, Ch.: Histochemical study on regional differences in the cholinergic nerve supply of the choroid plexus from various laboratory animals. Exp. Neurol. 55, 152–159 (1977)

    Google Scholar 

  • Lindvall, M., Edvinsson, L., Owman, Ch.: Sympathetic nervous control of cerebrospinal fluid production from the choroid plexus. Science 201, 176–178 (1978)

    Google Scholar 

  • Lindvall, M., Edvinsson, L., Owman, Ch.: Effect of sympathomimetic drugs and corresponding receptor antagonists on the rate of cerebrospinal fluid production. Exp. Neurol. (in press) (1979)

  • Lowry, O.H., Rosebrough, NJ., Farr, A.L., Randall, R.J.: Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265–274 (1951)

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lindvall, M. Fluorescence histochemical study on regional differences in the sympathetic nerve supply of the choroid plexus from various laboratory animals. Cell Tissue Res. 198, 261–267 (1979). https://doi.org/10.1007/BF00232009

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00232009

Key words

Navigation