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The morphology of uveal malignant melanomas

An in vitro study using the scanning electron microscope

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Abstract

Scanning electron microscopy (S.E.M.) has been performed on tissue cultures obtained from four choroidal malignant melanomas. The morphology of these cells has been demonstrated using this technique. Microvilli were found to present on the surfaces of all cells studied. These microprocesses often formed a connection between the cell and the cover slip, or other tumour cells. Rounded vesicles were demonstrated on the surfaces of some cells. It is possible that some of the larger vesicles contained melanosomes.

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References

  1. Barishak YR, Vanherick W, Yoneda C (1960) Tissue culture of uveal melanomas. Arch Ophthalmol 64:352–366

    Google Scholar 

  2. Callender GR (1931) Malignant melanotic tumours of the eye. A study of the histological types on III cases. Trans Am Acad Ophthalmol Otaloryngol 36:131–142

    Google Scholar 

  3. Mincione GP, Campana G, Vannelli G, Bonelli A (1979) Melanomes malins de l'uvee observes au microscope electronique a balayage. J Fr Ophthalmol 2, 10:527–530

    Google Scholar 

  4. Prause JU, Jensen OA (1980) Scanning electron microscopy of frozen-coated, dry cracked and enzyme digested tissue of human malignant choroidal melanomas. Albrecht v Graefes Arch Klin exp Ophthalmol 212:217–225

    Google Scholar 

  5. Radnot M (1976) Scanning electron microscopy of melanoblastomas of the choroid. Ophthalmologica 173:352–363

    Google Scholar 

  6. Radnot M (1977) Interzelluläre Verbindungen intraokularer Melanobastome. Klin Monatsbl Augenheilkd 170:868–873

    Google Scholar 

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Authors and Affiliations

  1. Department of Ophthalmology, St. Pauls Eye Hospital, Old Hall Street, L3 3PF, Liverpool, UK

    I. G. Rennie

  2. Department of Pathology, University of Sheffield Medical School, UK

    T. E. Durrant

  3. Department of Dermatology, University of Sheffield Medical School, UK

    L. S. Cawood

Authors
  1. I. G. Rennie
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  2. T. E. Durrant
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  3. L. S. Cawood
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Rennie, I.G., Durrant, T.E. & Cawood, L.S. The morphology of uveal malignant melanomas. Graefe's Arch Clin Exp Ophthalmol 219, 282–286 (1982). https://doi.org/10.1007/BF00231414

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  • DOI: https://doi.org/10.1007/BF00231414

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