Summary
The microsurgical implantation of a saphenous vascular axis into free transplanted autologous isolated rib segments in Beagle dogs led to complete revascularization of the bone after two, three and four weeks. Indian ink and Mercox-injected specimens showed a vascular network which penetrated the entire cortical layer. Semi-thin sections revealed osteoblasts and osteoclasts visible in the canals of the revascularized cortical layer, while the control specimen without vessel implantation showed nothing but ground substance. The revascularized bones did not contain any necrotic areas. The newly formed vascular system consisted of arteries, veins and their anastomoses. The veins appeared to produce a greater number of new vessels than the arteries.
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References
Allieu Y (1882) Les transfers osseux libres vascularisés. Rev Chir Orthop (Suppl) 68:44
Boyd RJ, Ault LL (1965) An experimental study of vascular implantation into the femoral head. Surg Gynecol Obstet 121:1009
Del Torto U, Zammini G (1967) Technic for arterial transplants into the growing distal epiphysis of femur. Int Surg 47:362
Dickerson RC, Duthie RB (1963) The diversion of arterial blood flow to bone. J Bone Joint Surg [Am] 45:356
Grishin JG, Lavrischeva GJ, Divakov MG (1983) Development of vascular net in implantation of vascular bundle into the avascular bone zones. Ortop Travmatol Protez (Russian) 8:5 (English Abstract)
Hori Y, Tamai S, Okuda H, Sakamota H, Takita T, Masuhara K (1975) Blood vessel transplantation to bone. J Hand Surg 4:23
Hutchinson M (1977) Injection techniques. In: Bancroft JB, Stevens A (eds) Theory and practice of histological technics. Churchill Livingstone, London, pp 402
Kien CL, Cebul F, Berg M, Gutentag JM, Glover DM (1984) A study of the vascularization of experimental bone grafts by means of radioactive phosphorus and the transparent chamber. Ann Plast Surg 12:287
Kleinert HE (1983) Bone and osteocutaneous microvascular free flaps. J Hand Surg 8:735
Krüger E, Lösch G (1964) Zur Frage der Bedeutung iiberlebender Zellen in autoplastischen Knochentransplantaten für die Osteogenese. Langenbecks Arch Klin Chir 306:77–86
Lalonde DH, Williams HB, Rosenthall L, Viloria JB (1984) Circulation, bone scans, and tetracyclin labeling in microvascularised and vascular bundle implanted rib grafts. Ann Plast Surg 13:366
Nettelblad H, Randolph MA, Östrup LT, Weiland AJ (1985) Molded vascularized osteogenesis: A preliminary study in rabbits. Plast Reconstr Surg 76:851
Ostrup LT (1982) Free bone transfers. Scand J Plast Reconstr Surg (Suppl) 19:103
Richardson KC, Jarett L, Finke EH (1960) Embedding in epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol 35:313–325
Šmahel J, Meyer VE, Valka J (1986) Implantation of a muscle flap in a free bone graft to promote revascularization. Chir Plastica 8:137
Taylor GJ (1983) The current status of free vascularized bone grafts. Clin Plast Surg 10:185
Valka J, Smahel J, Meyer VE (1984) Implantation of blood vessels into a free bone graft to promote its revascularization. Chir Plastica 8:37
Woodhouse ChF (1963) The transplantation of patent arteries to bone. Cardiovasc Surg 39:437
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Celebi, M.C., Winkel, R., Schramm, U. et al. Revascularization of isolated autologous bone grafts following microsurgical implantation of arteries and veins. Eur J Plast Surg 12, 29–34 (1989). https://doi.org/10.1007/BF00226918
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DOI: https://doi.org/10.1007/BF00226918