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Production of kojic acid from Aspergillus oryzae var.oryzae by membrane-surface liquid culture

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Biotechnology Techniques

Summary

Membrane-surface liquid culture (MSLC) developed by the authors (Yasuhara et al., 1994) was applied to the production of kojic acid, using Aspergillus oryzae var.oryzae IFO 30113. By the fed-batch MSLC with intermittent glucose addition, the amount of kojic acid increased to over 50 times that obtained by means of the culture in shake flasks.

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Authors and Affiliations

  1. Department of Biotechnology, Faculty of Engineering, Okayama University, Tsushima-naka, 700, Okayama, Japan

    A. Ogawa, Y. Morita, T. Tanaka, T. Sakiyama & K. Nakanishi

Authors
  1. A. Ogawa
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  2. Y. Morita
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  3. T. Tanaka
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  4. T. Sakiyama
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  5. K. Nakanishi
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Ogawa, A., Morita, Y., Tanaka, T. et al. Production of kojic acid from Aspergillus oryzae var.oryzae by membrane-surface liquid culture. Biotechnol Tech 9, 153–156 (1995). https://doi.org/10.1007/BF00224417

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  • DOI: https://doi.org/10.1007/BF00224417

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