Skip to main content
Log in

Complexes of annulate lamellae and nemaline bodies in soleplate nuclei in skeletal muscle fibers of the normal rat

  • Published:
Cell and Tissue Research Aims and scope Submit manuscript

Summary

Pseudointranuclear inclusions resulting from invaginations of the nuclear envelope, characteristic of myopathic muscles, were found in the soleplate nuclei of normal soleus muscles of rats. Such inclusions had annulate lamellae (AL), nemaline or rod bodies, lamellar structures, a concentric system of membranes, as well as tightly packed sarcoplasmic organelles. An accumulative origin of such included structures was suggested. The AL were sometimes connected directly to the outer membrane enclosing the inclusions, dilated into cisterns and positioned perpendicularly against the nuclear surface. AL, some of which were welldeveloped, were observed in the same loci as above during the course of denervation atrophy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Afzelius BA (1955) The ultrastructure of the nuclear membrane of the sea urchin oocytes as studied with the electron microscope. Exp Cell Res 8:147–158

    Google Scholar 

  • Bal AK, Jubinville F, Cousineau GH, Inoué S (1968) Origin and fate of annulate lamellae in Arbacia punctulata eggs. J Ultrastruct Res 25:15–28

    Google Scholar 

  • Beaulaton J (1968) Modifications ultrastructurales des cellules sécrétrices de la glande prothoracique de vers à soie, au cours des deux derniers âges larvaires. III. — Les lamelles annelées et leur dégradation. J Microsc 7:895–906

    Google Scholar 

  • Engel AG (1966) Late onset rod myopathy (a new syndrome?): Light and electron microscopic observations in two cases. Mayo Clin Proc 41:713–741

    Google Scholar 

  • Fardeau M (1973) Normal ultrastructural aspect of human motor endplate and its pathologic modifications. In: Desmet JE, Mostofi FK (eds) The striated muscle. Williams & Wilkins Comp, Baltimore, pp 342–363

    Google Scholar 

  • Franke WW (1974) Structure, biochemistry and functions of the nuclear envelope. Int Rev Cytol Suppl 4:71–235

    Google Scholar 

  • Gross BG (1966) Annulated lamellae in the axillary apocrine glands of adult man. J Ultrastruct Res 14:64–73

    Google Scholar 

  • Kawabuchi M (1980) Annulate lamellae in regenerating skeletal muscle fibers of rats treated with cholinesterase inhibitor. Cell Biol Int Repts 4:691–695

    Google Scholar 

  • Kessel RG (1968) Annulate lamellae. J Ultrastruct Res Suppl 10:1–82

    Google Scholar 

  • Kleinfeld RG, Greider MH, Frajola WJ (1956) Electron microscopy of intranuclear inclusions found in human and rat liver parenchymal cells. J Biophys Biochem Cytol Suppl 2:435–438

    Google Scholar 

  • Leduc EH, Wilson JW (1959a) A histochemical study of intranuclear inclusions in mouse liver and hepatoma. J Histochem Cytochem 7:8–16

    Google Scholar 

  • Leduc EH, Wilson JW (1959b) An electron microscope study of intranuclear inclusions in mouse liver and hepatoma. J Biophys Biochem Cytol 6:427–430

    Google Scholar 

  • Lee JC, Altschul R (1963) Electron microscopy of the nuclei of denervated skeletal muscle. Z Zellforsch 61:168–182

    Google Scholar 

  • Manolov S, Ovtscharoff W (1973) Ultrastructural changes in the nuclei of denervated muscles in the rat. Z mikrosk anat Forsch 87:815–828

    Google Scholar 

  • Maul GO (1977) The nuclear and the cytoplasmic pore complex: structure, dynamics, distribution, and evolution. Int Rev Cytol Suppl 6:75–186

    Google Scholar 

  • McCulloch D (1952) Fibrous structures in the ground cytoplasm of the arbacia egg. J Exp Zool 119:47–64

    Google Scholar 

  • Merkow L, Leighton J (1966) Increased numbers of annulate lamellae in myocardium of chick embryos incubated at abnormal temperatures. J Cell Biol 28:127–137

    Google Scholar 

  • Merriam RW (1959) The origin and fate of annulate lamellae in maturing sand dollar eggs. J Biophys Biochem Cytol 5:117–121

    Google Scholar 

  • Miledi R, Slater CR (1968) Electrophysiology and electron-microscopy of rat neuromuscular junctions after nerve degeneration. Proc Roy Soc B 169:289–306

    Google Scholar 

  • Miledi R, Slater CR (1969) Electron-microscopic structure of denervated skeletal muscle. Proc Roy Soc B 174:253–269

    Google Scholar 

  • Padykula HA, Gauthier GF (1970) The ultrastructure of the neuromuscular junctions of mammalian red, white, and intermediate skeletal muscle fibers. J Cell Biol 46:27–41

    Google Scholar 

  • Pellegrino C, Franzini C (1963) An electron microscope study of denervation atrophy in red and white skeletal muscle fibers. J Cell Biol 17:327–349

    Google Scholar 

  • Price HM (1973) Ultrastructural pathologic characteristics of the skeletal muscle fiber: an introductory survey. In: Desmedt JE, Motofi FK (eds) The striated muscle. Williams & Wilkins Comp, Baltimore, pp 144–184

    Google Scholar 

  • Rebhun LI (1956) Electron microscopy of basophilic structures of some invertebrate oocytes. I. Periodic lamellae and the nuclear envelope. J Biophys Biochem Cytol 2:93–104

    Google Scholar 

  • Ross MH (1962) Annulate lamellae in the adrenal cortex of the fetal rat. J Ultrastruct Res 7:373–382

    Google Scholar 

  • Santa T, Engel AG (1973) Histometric analysis of neuromuscular junction ultrastructure in rat red, white and intermediate muscle fibers. In: Desmedt JE (ed) New developments in electromyography and clinical neurophysiology. Karger S, New York, pp 41–54

    Google Scholar 

  • Smith FE, Berlin JD (1977) Cytoplasmic annulate lamellae in human spermatogenesis. Cell Tissue Res 176:235–242

    Google Scholar 

  • Sobel HJ, Schwarz R, Marquet E (1969) Nonviral nuclear inclusions. I. Cytoplasmic invaginations. Arch Pathol 87:179–192

    Google Scholar 

  • Swift H (1956) The fine structure of annulate lamellae. J Biophys Biochem Cytol Suppl 2:415–418

    Google Scholar 

  • Wessel W (1958) Elektronenmikroskopische Untersuchungen von intranucleären Einschlußkörpern. Virchow Arch Path Anat 331:314–328

    Google Scholar 

  • Wischnitzer S (1970) The annulate lamellae. Int Rev Cytol 27:65–100

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kawabuchi, M. Complexes of annulate lamellae and nemaline bodies in soleplate nuclei in skeletal muscle fibers of the normal rat. Cell Tissue Res. 231, 337–346 (1983). https://doi.org/10.1007/BF00222185

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00222185

Key words

Navigation