Abstract
Data on egg weight from experimental crosses with two inbred lines of chickens suggested evidence for segregation of a single dominant major gene. Because the data could not be transformed to satisfy normality and homoscedasticity conditions, the non-parametric test of Elston and the graphical approach used by Stolk et al. were applied. Due to a bad fit of the backcross B2 (P2×F1) and the F2 groups, both methods reject the hypothesis of a dominant major gene as the the only cause of the differences in egg weight between the six genetic groups involved.
Similar content being viewed by others
References
Box GEP, Cox DR (1964) An analysis of transformations. J Roy Stat Soc (B) 26:211–252
Elston RC (1981) Testing one- and two-locus hypotheses for the genetic difference of a quantitative trait between two homozygous lines. In: Gershon ES, Matthysse S, Brakefield XO, Ciaranello RD (ed) Genetic research strategies for psychobiology and psychiatry. The Boxwood Press, Pacific Grove, California, pp 283–293
Elston RC (1984) The genetic analysis of quantitative trait differences between two homozygous lines. Genetics 108:733–744
Elston RC, Stewart J (1973) The analysis of quantitative traits for simple genetic models from parental, F1 and backcross data. Genetics 73:695–711
Falconer DS (1981) Introduction to quantitative genetics, 2nd edn. Longman, Inc., New York
Hagger C (1985) Line and crossing effects in a diallel mating system with highly inbred lines of Whilte Leghorn chickens. Theor Appl Genet 70:555–560
Hagger C, Stranzinger G (1992) A method to detect large influences of specific sex chromosomes on quantitative traits. Theor Appl Genet 83:925–929
Le Roy P, Elsen JM (1992) Simple test statistics for major gene detection: a numerical comparison. Theor Appl Genet 83:635–644
Stewart J, Elston RC, (1973) Biometrical genetics with one or two loci: the inheritance of physiological characters in mice. Genetics 73:675–693
Stolk JM, Vantini G, Guchhait RB, Hurst JH, Perry BD, U'Pritchard DC, Elston RC (1984) Inheritance of adrenalin phenylethanolamine n-methyltransferase activity in the rat. Genetics 108:633–649
Author information
Authors and Affiliations
Additional information
Communicated by E. J. Eisen
Rights and permissions
About this article
Cite this article
Hagger, C., Stricker, C., Elston, R.C. et al. Lack of evidence for segregation of a single dominant major gene as the cause of the difference in egg weight between two highly inbred lines of chickens. Theoret. Appl. Genetics 90, 120–123 (1995). https://doi.org/10.1007/BF00221004
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00221004