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Histochemistry of the juxtaglomerular apparatus in the toad Bufo bufo

The glucose-6-phosphate dehydrogenase activity of the macula densa

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Summary

An investigation regarding the question of whether there exists a macula densa as part of the juxtaglomerular apparatus in the kidney of amphibians has been carried out. With the aid of a histochemical reaction for glucose-6-phosphate dehydrogenase activity, the presence of a macula densa zone as a specialized part of the distal tubule in the toad Bufo bufo was demonstrated. The functional significance of the high glucose-6-phosphate dehydrogenase activity in the macula densa cells is discussed.

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Authors and Affiliations

  1. Biological Laboratory Medical Faculty, University of Nijmegen, The Netherlands

    A. P. M. Lamers & G. J. A. Speijers

  2. Laboratory for Submicroscopic Morphology, Medical Faculty, University of Nijmegen, The Netherlands

    A. M. Stadhouders

  3. Biological Laboratory, Medical Faculty, Geert Grooteplein Noord 21, Nijmegen, The Netherlands

    A. M. Stadhouders

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  1. A. P. M. Lamers
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  2. G. J. A. Speijers
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  3. A. M. Stadhouders
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Lamers, A.P.M., Speijers, G.J.A. & Stadhouders, A.M. Histochemistry of the juxtaglomerular apparatus in the toad Bufo bufo . Cell Tissue Res. 184, 435–444 (1977). https://doi.org/10.1007/BF00220967

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