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Immunofluorescence study of LH-RH producing cells in the human fetal hypothalamus

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Summary

The use of antibodies to synthetic LH-RH has enabled the detection by immunofluorescence of hypothalamic LH-RH producing cells in the human fetus. The perikarya of these cells are located in the pericommissural and preoptic regions, in the lamina terminalis and in the premamillary region. Reactive axons occur in the median eminence. The first LH-RH producing cells are seen as early as nine weeks of gestation. The specificity of immunocytological reaction has been controlled.

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Authors and Affiliations

  1. Laboratoire d'Histologie et Embryologie, U.E.R. Médicale Lyon Sud-Ouest, Oullins, France

    C. Paulin & P. M. Dubois

  2. Station de Physiologie de la Reproduction, INRA, Nouzilly, France

    M. P. Dubois

  3. Laboratoire d'Histologie, Faculté de Médecine, Lille, France

    J. Barry

Authors
  1. C. Paulin
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  2. M. P. Dubois
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  3. J. Barry
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  4. P. M. Dubois
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Paulin, C., Dubois, M.P., Barry, J. et al. Immunofluorescence study of LH-RH producing cells in the human fetal hypothalamus. Cell Tissue Res. 182, 341–345 (1977). https://doi.org/10.1007/BF00219769

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