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Action of staphylococcal α-toxin on membranes: Some recent advances

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Summary

Recent developments in the area of Staphylococcal α-toxin studies are presented which modify the concepts previously held with respect to both biological and physical properties of α-toxin. New data concerning the nature of the binding site for α-toxin on rabbit erythrocyte membranes and a model to explain the various observed complexes of α-toxin and membrane receptor are discussed. Finally, evidence suggesting that Staphylococcal α-toxin is a potent demyelinating agent is presented.

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Authors and Affiliations

  1. Department of Microbiology, School of Medicine, Vanderbilt University Nashville, 37232, Tennessee

    Sidney Harshman

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  1. Sidney Harshman
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The work was supported in part by NSF grant PCM 77-19307

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Harshman, S. Action of staphylococcal α-toxin on membranes: Some recent advances. Mol Cell Biochem 23, 143–152 (1979). https://doi.org/10.1007/BF00219453

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  • DOI: https://doi.org/10.1007/BF00219453

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