Summary
The development of noradrenergic innervation was studied in the mouse heart using fluorescence histochemistry. Following incubation of hearts with α-methylnoradrenaline fluorescent nerve fibres were seen as early as 13 days in utero. It is suggested that the neuronal uptake mechanism for noradrenaline is functional at an early stage.
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Mackenzie, E., Standen, N.B. Adrenergic innervation of the mouse heart revealed at an early stage using α-methylnoradrenaline. Cell Tissue Res. 173, 129–132 (1976). https://doi.org/10.1007/BF00219270
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DOI: https://doi.org/10.1007/BF00219270