Summary
Atrial myoendocrine cells of rat were investigated regarding estradiol uptake. It was found that, in addition to their specific endocrine function of producing cardiac polypeptides of the cardiodilatin/atrial natriuretic peptide (CDD/ANP) family, these cells also specifically accumulate radiolabeled estradiol. This co-localization supports the view that steroid hormones play an important role in the regulation of the CDD/ANP gene.
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References
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Back, H., Forssmann, W.G. & Stumpf, W.E. Atrial myoendocrine cells (cardiodilatin/atrial natriuretic polypeptide-containing myocardiocytes) are target cells for estradiol. Cell Tissue Res. 255, 673–674 (1989). https://doi.org/10.1007/BF00218808
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DOI: https://doi.org/10.1007/BF00218808