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Freeze-etching studies on ultrastructural changes of endothelial cells in the thyroid of normal, TSH-treated and Thyradin-treated mice

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Summary

Freeze-etching images of the capillary endothelium in the thyroid of normal, TSH-treated and Thyradin (powdered thyroid)-treated mice were examined. Numerous pores represent vesicular stomata or fenestrations. The number of the pores and their population density are increased in TSH-treated mice, and decreased in Thyradin-treated animals. In addition, the width of the parajunctional zone and of the flat ray free from endothelial pores is smaller in TSH-treated mice and larger in Thyradin-treated animals. These facts indicate that the number of endothelial pores changes according to the functional activity of the gland.

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Ishimura, K., Okamoto, H. & Fujita, H. Freeze-etching studies on ultrastructural changes of endothelial cells in the thyroid of normal, TSH-treated and Thyradin-treated mice. Cell Tissue Res. 175, 313–317 (1976). https://doi.org/10.1007/BF00218709

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