Summary
The grey level index (= GLI) and the fresh volume were determined with the image analyser Micro-Videomat for the nucl. n. facialis after axotomy of the left n. facialis. The experiments were performed on 10 rats in different stages of ontogenesis. The GLI is a quantitative parameter which could be quickly obtained and which demonstrated quantitative changes during retrograde reaction in the respective centres. A decrease in the fresh volumes of the affected nucl. n. facialis could also be demonstrated. The meaning of GLI is discussed.
Similar content being viewed by others
References
Cammermeyer, J.: Peripheral chromatolysis after transection of mouse facial nerve. Acta neuropath. (Berl.) 2, 213–236 (1963a)
Cammermeyer, J.: Differential response of two neuron types to facial nerve transection in young and old rabbits. J. Neuropath. exp. Neurol. 22, 594–616 (1963b)
Courville, J.: The nucleus of the facial nerve; the relation between cellular groups and peripheral branches of the nerve. Brain. Res. 1, 338–354 (1966)
Fernando, D.A.: An electron microscopic study of the neuroglial reaction in the hypoglossal nucleus after transection of the hypoglossal nerve. Acta anat. (Basel) 86, 1–14 (1973)
Hall, E.K., Schneiderhan, M.A.: Spinal ganglion hypoplasia after limb amputation in the fetal rat. J. comp. Neurol. 82, 19–34 (1945)
Haug, H.: Remarks on the determination and significance of the gray cell coefficient. J. comp. Neurol. 104, 473–492 (1956)
Lavelle, A.: Levels of maturation and reactions to injury during neuronal development. Prog. Brain Res. 40, 161–166 (1973)
Lavelle, A., Lavelle, F.W.: The nucleolar apparatus and neuronal reactivity to injury during development. J. exp. Zool. 137, 285–315 (1958)
Lavelle, A., Lavelle, F.W.: Neuronal swelling and chromatolysis as influenced by the state of cell development. Amer. J. Anat. 102, 219–241 (1958b)
Lavelle, A., Lavelle, F.W.: Neuronal reaction to injury during development: Severance of the facial nerve in utero. Experimental Neurology 1, 92–95 (1959)
Lavelle, A., Smoller, C.G.: Neuronal swelling and protein distribution after injury to developing neurons. Amer. J. Anat. 106, 97–107 (1960)
Nissl, F.: Über die Veränderungen der Ganglienzellen am Facialiskern des Kaninchens nach Ausreißung der Nerven. Allg. Z. Psychiat. 48, 197–198 (1892)
Papez, J.W.: Subdivisions of the facial nucleus. J. comp. Neurol. 43, 159–191 (1927)
Schleicher, A., Zilles, K., Kretschmann, H.J.: Automatische Registrierung und Auswertung eines Grauwertindex in histologischen Schnitten (in preparation)
Ščitkov, K.G.: Veränderungen in den motorischen Zellen des Rückenmarkes bei einseitiger Extremitätenamputation. Arch. pathol. 29–33 (1959)
Sumner, B.E.H., Sutherland, F.I.: Quantitative electron microscopy on the injured hypoglossal nucleus in the rat. J. Neurocytol. 2, 315–328 (1973)
Wingert, F.: Biometrische Analyse der Wachstumsfunktion von Hirnteilen und Körpergewicht der Albinomaus. J. Hirnforsch. 11, 133–197 (1969)
Zilles, K., Schleicher, A., Kretschmann, H.J.: A quantitative approach to cytoarchitectonics. I. The areal pattern of the cortex of Tupaia belangen. Anat. Embryol. (in press)
Author information
Authors and Affiliations
Additional information
Dedicated to Prof. Dr. H. Leonhardt on the occasion of his 60th birthday
Supported by Deutsche Forschungsgemeinschaft grants Kr 289/10 and Zi 192/1
Rights and permissions
About this article
Cite this article
Zilles, K., Schleicher, A. & Kretschmann, H.J. Automatic morphometric analysis of retrograde changes in the nucleus n. facialis at different ontogenetic stages in the rat. Cell Tissue Res. 190, 285–299 (1978). https://doi.org/10.1007/BF00218176
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00218176