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Isoforms of troponin during regeneration of chicken skeletal muscle fibers after cold injury

Cell and Tissue Research volume 236, pages 549–554 (1984)Cite this article

Summary

The regeneration of skeletal muscle fibers of the adult chicken was examined after a focal injury brought about with a liquid-nitrogen cooled brass rod. Immunofluorescence microscopy with antibodies specific for troponin (TN) components (T, I, and C) from adult chicken breast and ventricular muscles showed the presence of different fiber types in both the anterior and posterior latissimus dorsi muscles. New fibers produced in the regions adjacent to the site of injury in both muscles exhibited the same immunoreactivities as those previously seen in embryonic skeletal muscles. As differentiation proceeded, regenerating cells lost their embryonic antigenicities and recovered their characteristic adult reactivities. These results indicate that, during regeneration from cold injury, skeletal muscles apparently pass again through an embryonic stage during which they synthesize embryonic-like TN isoforms.

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Author notes

  1. Naoji Toyota

    Present address: Division of Neurochemistry, Psychiatric Research Institute of Tokyo, Kamikitazawa, Setagaya, 156, Tokyo, Japan

Affiliations

  1. Department of Anatomy, School of Medicine, Chiba University, Chiba, Japan

    Naoji Toyota &  Yutaka Shimada

Authors
  1. Naoji Toyota
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  2. Yutaka Shimada
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Toyota, N., Shimada, Y. Isoforms of troponin during regeneration of chicken skeletal muscle fibers after cold injury. Cell Tissue Res. 236, 549–554 (1984). https://doi.org/10.1007/BF00217221

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  • DOI: https://doi.org/10.1007/BF00217221

Key words

  • Troponin-T, -I, and -C
  • Regeneration
  • Skeletal muscle