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Comparative study of structure and function of blood cells from two Drosophila species

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Hemocytes of Drosophila melanogaster and Drosophila yakuba larvae have been defined in terms of their ultrastructure and functions in “coagulation”, wound healing, encapsulation, phenol-oxydase activity, and phagocytosis. The position of these cells among the classical hemocyte types of insects is determined. We distinguish two plasmatocyte types (macrophage plasmatocytes and lamellocytes) which do not seem to belong to the same lineage, and oenocytoids which are the crystal cells of the literature.

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  • Akaï H, Sato S (1973) Ultrastructure of the larval hemocytes of the silkworm, Bombyx mori L. (Lepidoptera, Bombycidae). Int J Insect Morphol Embryol 2:207–231

    Google Scholar 

  • Beaulaton J, Monpeyssin M (1977) Ultrastructure et cytochimie des hémocytes d' Antheraea pernyi Guér. (Lepidoptera, Attacidae). II. Cellules à sphérules et oenocytoïdes. Rev Biol Cell 28:13–18

    Google Scholar 

  • Brehélin M (1977) Etude morphologique et fonctionnelle des hémocytes d'Insectes. Thèse d'Etat, n° 1065, Strasbourg

  • Brehélin M, Hoffmann J (1980) Phagocytosis of inert particles in Locusta migratoria and Galleria mellonella: study of ultrastructure and clearance. J Insect Physiol 26:103–111

    Google Scholar 

  • Brehélin M, Zachary D, Hoffmann J (1978) A comparative ultrastructural study of blood cells from nine insect orders. Cell Tissue Res 195:45–57

    Google Scholar 

  • Carton Y, Kitano H (1979) Changes in the hemocyte population of Drosophila larvae after single and multiple parasitization by Cothonaspis (parasitic Cynipidae). J Invertebr Pathol 34:88–89

    Google Scholar 

  • Crossley AC (1975) The cytophysiology of insect blood. Adv Insect Physiol 11:117–222

    Google Scholar 

  • Crossley AC (1979) Biochemical and Ultrastructural aspects of synthesis, storage and secretion in hemocytes. In: Gupta AP (ed) Insect Hemocytes. Cambridge University Press

  • David J (1959) Etude quantitative du développement de la Drosophile élevée en milieu axénique. Bull Biol Fr Belg 93:472–505

    Google Scholar 

  • L'Héritier P (1952) A convenient device for injecting large number of flies Drosophila. Information service 26:131

    Google Scholar 

  • Martoja R, Martoja M (1967) Initiation aux techniques de l'histologie animale. Masson et Cie (eds)

  • Nappi AJ (1970) Hémocytes of larvae of Drosophila euronotus (Diptera, Drosophilidae). Ann Entomol Soc Amer 63:1217–1224

    Google Scholar 

  • Neuwirth M (1974) Granular hemocytes, the main phagocytic blood cells in Calpodes ethlius (Lepidoptera Hesperiidae). Can J Zool 52:783–784

    Google Scholar 

  • Nordlander M (1980) Revision of the genus Leptopilina (Forster1869) with notes on status of some other genera (Hymenoptera Cynipoidea, Eucoilidae). Ent. Scand 11:428–453

    Google Scholar 

  • Ratcliffe NA, Gagen SJ (1977) Studies on the in vivo cellular reactions of insects: an ultrastructural analysis of nodule formation in Galleria mellonella. Tissue & Cell 9:73–85

    Google Scholar 

  • Rizki TM (1978) The circulatory system and associated cells and tissues. In: Ashburner M, Wright TRF (eds) The genetics and biology of Drosophila. Academic Press, New York

    Google Scholar 

  • Rizki TM, Rizki RM (1959) Functional significance of Crystal cells in the larva of Drosophila melanogaster. J Biophysic Biochem Cytol 5:235–244

    Google Scholar 

  • Rizki TM, Rizki RM (1980) Properties of the larval hemocytes of Drosophila melanogaster. Experientia 36:1223–1226

    Google Scholar 

  • Srdič Z, Gloor H (1978) Le rôle hématopoïétique des glandes lymphatiques de Drosophila hydei. Rev Suisse Zool. 85:11–19

    Google Scholar 

  • Srdič Z, Gloor H (1979) Spherule cells in Drosophila species. Experientia 35:1246–1249

    Google Scholar 

  • Vercauteren RE, Aerts F (1958) On the cytochemistry of the hemocytes of Galleria mellonella with special reference to polyphenoloxydase. Enzymologia 10:167–172

    Google Scholar 

  • Yu CH, Yang HY, Kim WK, Kim CW (1976) Electron microscopic studies on the larval hemocytes of Drosophila melanogaster. Korean J Zool 19:143–154

    Google Scholar 

  • Zachary D, Hoffman J (1973) The hemocytes of Calliphora erythrocephala. Z Zellforsch 141:55–73

    Google Scholar 

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I should like to thank Dr. N. Plus for her help in this study

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Brehélin, M. Comparative study of structure and function of blood cells from two Drosophila species . Cell Tissue Res. 221, 607–615 (1982).

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