References
Ashwell, J. D. and Klausner, R. D.: Genetic and mutational analysis of the T-cell antigen receptor. Annu Rev Immunol 8: 139–167, 1990
Campbell, K. S. and Cambier, J. C.: B lymphocyte antigen receptors (mIg) are non covalently associated with a disulfide linked, inducibly phosphorylated glycoprotein complex. EMBO J 9: 441–448, 1990
Campbell, K. S., Hager, E. J., Friedrich, J. R., and Cambier, J. C.: The IgM antigen receptor complex is associated with phosphoprotein products of B29 and mb-1 genes. Proc Natl Acad Sci USA 88: 3982–3986, 1991
Campbell, M.-A. and Sefton, B. M.: Protein tyrosine phosphorylation is induced in murine B lymphocytes in response to stimulation with anti-immunoglobulin. EMBO J 9: 2125–2132, 1990
Chen, J., Stall, A. M., and Herzenberg, L. A.: Differences in glycoprotein complexes associated with IgM and IgD on normal murine B cell potentially enable transduction of different signals. EMBO J 9: 2117–2124, 1990
Clevers, H. C., Alarcon, B., Wileman, T. E., and Terhorst, C.: The T-cell receptor/CD3 complex: a dynamic protein ensemble. Annu Rev Immunol 6: 629–662, 1988
Feinberg, A. P. and Vogelstein, B.: A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 132: 6–13, 1983
Gold, M. R., Matsuuchi, L., Kelly, R. B., and De Franco, A. L.: Tyrosine phosphorylation of components of the B cell antigen receptor following receptor crosslinking. Proc Natl Acad Sci USA 88: 3436–3440, 1991
Hermanson, G. G., Eisenberg, D., Kincade, P. W., and Wall, R.: B29: A member of the immunoglobulin gene superfamily exclusively expressed on B-lineage cells. Proc NatlAcad Sci USA 85: 6890–6894, 1988
Hombach, J., Leclercq, L., Radbruch, A., Rajewsky, K., and Reth, M.: A novel 34kD protein co-isolated with IgM Molecule in surface IgM expressing cells. EMBO J 7: 3 51–3456, 1988
Hombach, J., Tsubata, T., Leclercq, L., Stappert, H., and Reth, M.: Molecular components of the B cell antigen receptor complex of the IgM class. Nature 343: 760–762, 1990a
Hombach, J., Lottspeich, F., and Reth, M.: Identification of the genes encoding the IgM-α and Ig-β components of the B cell antigen receptor complex by aminos-terminal sequencing. Eur J Immunol 20: 2795–2799, 1990b
Kashiwamura, S-i., Koyama, T., Matsuo, T., Steinmetz, M., Kimoto, M., and Sakaguchi, N.: Structure of the murine mb-1 gene encoding a putative sIgM-associated molecule. J Immunol 145: 337–343, 1990
Parkhouse, R. M. E.: Three B-cell surface molecules associating with membrane immunoglobulin. Immunology 69: 298–302, 1990
Reth, M., Hombach, J., Wienands, J., Campbell, K. S., Chien, N., Justement, L. B., and Cambier, J. C.: The B-cell antigen receptor complex. Immunol Today 12: 196–201, 1991
Reth, M.: Antigen receptor tail clue. Nature 338: 383–384, 1989
Sakaguchi, N., Kashiwamura, S-i., Kimoto, M., Thalmann, P., and Melchers, F.: B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like properties. EMBO J 7: 3457–3464, 1988
Sanger, F., Nicklen, S., and Coulson, A. R.: DNA Sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74: 5463–5467, 1977
Van Noesel, C. J. M., van Lier, R. A. W., Cordell, J. L., Tse, A. G. D., van Schijndel, G. M. W., de Vries, E. F. R., Mason, D. Y., and Borst, J.: The membrane IgM associated heterodimer on human B cells is a newly defined B cell antigen that contains the protein product of the mb-1 gene. J Immunol 146: 3881–3888, 1991
Van Noesel, C. J. M., Borst, J., de Vries, E. F. R., and van Lier, R. A. W.: Identification of two distinct phosphoproteins as components of the human B-cell antigen receptor complex. Eur J Immunol 20: 2789–2793, 1990
Venkitaraman, A. R., Williams, G. T., Dariavach, P., and Neuberger, M. S.: The B-cell antigen receptor of the five immunoglobulin classes. Nature 352: 777–781, 1991
Wienands, J., Hombach, J., Radbruch, A., Riesterer, C., and Reth, M.: Molecular components of the B cell antigen receptor complex of class IgD differ partly from those of IgM. EMBO J 9: 449–445, 1990
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The nucleotide sequence data reported in this paper have been submitted to the GenBank nucleotide sequence database and have been assigned the accession number M74721.
Address correspondence and offprint requests to: M. Reth.
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Flaswinkel, H., Reth, M. Molecular cloning of the Ig-α subunit of the human B-cell antigen receptor complex. Immunogenetics 36, 266–269 (1992). https://doi.org/10.1007/BF00215058
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DOI: https://doi.org/10.1007/BF00215058