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Formation of autophagosomes in the pinealocytes of the rat and Mongolian gerbil (Meriones unguiculatus): A lysosome wrapping mechanism?

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Summary

Autophagosome formation in rat and gerbil pinealocytes is described. It starts with the setting up of a tubular acid phosphatase-rich cisterna which gradually wraps around cytoplasmic areas to be catabolized. In light of obtained findings, it seems that the autophagosome formation in pinealocytes is a type of lysosome wrapping mechanism.

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References

  • Arstila AU (1967) Electron microscopic studies on the structure and histochemistry of the pineal gland of the rat. Neuroendocrinology 2 (Suppl): 1–100

    Google Scholar 

  • Bucana CD, Nadakavukaren MJ, Frehn JL (1973) Ultrastructural features of the pineal gland from cold-exposed golden hamsters. J Neurocytol 2:237–247

    Google Scholar 

  • Calvo J, Boya J (1983) Postnatal development of cell types in the rat pineal gland. J Anat 137:185–195

    Google Scholar 

  • Clabough JW (1971) Ultrastructural features of the pineal gland in normal and light deprived golden hamsters. Z Zellforsch 114:151–164

    Google Scholar 

  • Forssmann WG, Siegrist G, Orci L, Girardier L, Pictet R, Rouiller C (1967) Fixation par perfusion pour la microscopie électronique. Essai de généralisation. J Microsc 6:279–304

    Google Scholar 

  • Karasek M, Wyrzykowski Z (1980) The ultrastructure of pinealocytes in the pig. Cell Tissue Res 211:151–161

    Google Scholar 

  • Lin HS, Hwang BH, Tseng CY (1975) Fine structural changes in the hamster pineal gland after blinding and superior cervical ganglionectomy. Cell Tissue Res 158:285–299

    Google Scholar 

  • Mayahara H (1972) Ultracytochemistry of mouse subcutaneous histiocytes. 2. Mechanism of autophagolysosome formation. J Kansai Med School: Suppl 98–129

  • Mayahara H, Ogawa K (1972) Lysosomal wrapping mechanism observed in the autophagolysome formation. In: Takeuchi T, Ogawa K, Fujita S (eds) Histochemistry and cytochemistry 1972. Jpn Soc Histochem Cytochem, Kyoto, pp 29–30

    Google Scholar 

  • McNeill ME (1978) Membranous structures in pinealocytes of the infertile diabetic mutant mouse (C 57 BL/Ks-db/db). J Neural Transm 42:207–221

    Google Scholar 

  • Novikoff PM, Novikoff AB, Quintana N, Hauw JJ (1971) Golgi apparatus, GERL, and lysosomes of neurons in rat dorsal root ganglia, studied by thick section and thin section cytochemistry. J Cell Biol 50:859–886

    Google Scholar 

  • Ogawa K (1981) Lysosomal wrapping mechanism (LWM) during autophagy. Acta Histochem Cytochem 14:362–365

    Google Scholar 

  • Pévet P (1974) The pineal gland of the mole (Talpa europaea L.). I. The fine structure of the pinealocytes. Cell Tissue Res 153:277–292

    Google Scholar 

  • Pévet P, Racey PA (1981) The pineal gland of nocturnal mammals. II. The ultrastructure of the pineal gland in the pipistrelle bat (Pipistrellus pipistrellus L.): Presence of two populations of pinealocytes. Cell Tissue Res 216:253–271

    Google Scholar 

  • Pévet P, Saboureau M (1973) L'épiphyse du hérisson (Erinaceus europaeus L.) mâle. I. Les pinéalocytes et leurs variations ultrastructurales considérées au cours du cycle sexuel. Z Zellforsch 143:367–385

    Google Scholar 

  • Pévet P, Ariëns Kappers J, Nevo E (1976) The pineal gland of the mole-rat (Spalax ehrenbergi, Nehring). I. The fine structure of pinealocytes. Cell Tissue Res 174:1–24

    Google Scholar 

  • Pévet P, Ariëns Kappers J, Voûte AM (1977) The pineal gland of nocturnal mammals. I. The pinealocytes of the bat (Nyctalus noctula, Schreber). J Neural Transm 40:47–68

    Google Scholar 

  • Robinson JM, Karnovsky MJ (1983) Ultrastructural localization of several phosphatases with cerium. J Histochem Cytochem 31:1197–1208

    CAS  PubMed  Google Scholar 

  • Romijn HJ (1975) The ultrastructure of the rabbit pineal gland after sympathectomy, parasympathectomy, continuous illumination, and continuous darkness. J Neural Transm 36:183–194

    Google Scholar 

  • Sakai M, Ogawa K (1984) Relationship between lysosomal wrapping mechanism (LWM) and cytoskeletal elements during autophagolysosome formation. Acta Histochem Cytochem 17:1–13

    Google Scholar 

  • Wolfe DE (1965) The epiphyseal cell: an electron-microscopic study of its intercellular relationships and intracellular morphology in the pineal body of the albino rat. In: Ariëns Kappers J, Schadé JP (eds) Structure and function of the epiphysis cerebri. Prog Brain Res, Vol. 10. Elsevier, Amsterdam London New York, pp 332–376

    Google Scholar 

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  1. Faculty of Medicine, Institute of Histology and Embryology, Lausanne-CHUV, Switzerland

    Radivoj Krstić

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  1. Radivoj Krstić
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Krstić, R. Formation of autophagosomes in the pinealocytes of the rat and Mongolian gerbil (Meriones unguiculatus): A lysosome wrapping mechanism?. Cell Tissue Res. 241, 677–681 (1985). https://doi.org/10.1007/BF00214591

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  • DOI: https://doi.org/10.1007/BF00214591

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