Skip to main content
Log in

Ordering of markers in the pericentromeric region of chromosome 10

  • Short Communication
  • Published:
Human Genetics Aims and scope Submit manuscript

Abstract

Seven polymorphic cosmids previously assigned to 10cen-q11.2 were mapped between D10S34 and RBP3, and ordered by interphase in situ hybridization and yeast artificial chromosome analysis. Some of the presumed unique sequences from the centromeric region have homologies either within the same region or within the centromeric region of other chromosomes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Fisher JH, Emrie PA, Drabkin HA, Kushnik T, Gerber M, Hofmann T, Jones C (1988) The gene encoding the hydrophobia surfactant protein SP-C is located on 8p and identifies an EcoRI RFLP. Am J Hum Genet 43:436–441

    Google Scholar 

  • Martucciello G, Biocchi MP, Dodero P, Lerone M, Silengo Cirillo M, Puliti A, Gimelli G, Romeo G, Jasoni V (1992) Total colonic aganglionosis associated with interstitial deletion of the long arm of chromosome 10. Pedatr Surg Int 7:308–310

    Google Scholar 

  • Mathew CGP, Wakeling W, Jones E, Easton E, Fisher R, Strong C, Smith B, Chin K, Little P, Nakamura Y, Shows TB, Jones C, Goodfellow PJ, Povey S, Ponder BAJ (1990) Regional localization of polymorphic markers on chromosome 10 by physical and genetic mapping. Ann Hum Genet 54:121–129

    Google Scholar 

  • Mole S, Jackson MS, Tokino T, Nakamura Y, Ponder BAJ (1993) Assignment of fifty-four cosmid clones to five regions of chromosome 10. Genomics 15:457–458

    Google Scholar 

  • Nakamura Y, Lathrop M, Bragg T, Leppert M, O'Connell P, Jones C, Lalouel JM, White R (1988) An extended genetic linkage map of markers for human chromosome 10. Genomics 3:389–392

    Google Scholar 

  • Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

    Google Scholar 

  • Taanman JW, Veen AY van der, Schrage C, Vries H de, Buys CHCM (1991) Assignment of the gene coding for human cytochrome c oxidase subunit VIb to chromosome 19, band q13.1, by fluorescence in situ hybridisation. Hum Genet 87: 325–327

    Google Scholar 

  • Tokino T, Takiguchi S, Tanigami A, Bragg T, Jones C, Nakamura Y (1992a) Thirty-one new RFLP systems detected by twentyfour DNA markers on human chromosome 10. Genomics 12:401–402

    Google Scholar 

  • Tokino T, Imai T, Tanigami A, Takiguchi S, Nakamura Y (1992b) Physical mapping of a 950-kb region surrounding a locus (D10S102) tightly linked to the MEN2A gene. Genomics 12:394–400

    Google Scholar 

  • Tunnacliffe A, Liu L, Moore JK, Leversha MA, Jackson MS, Papi L, Ferguson-Smith MA, Thiesen HJ, Ponder BAJ (1993) Duplicated KOX zinc finger gene cluster flanks the centromere of human chromosome 10: evidence for a pericentromeric inversion during primate evolution. Nucleic Acids Res 21: 1409–1417

    Google Scholar 

  • Wiegant J, Kalle W, Mullenders L, Brookes S, Hoovers JMN, Dauwerse JG, Ommen GJB van, Raap AK (1992) High-resolution in situ hybridization using DNA halo preparations. Hum Mol Genet 1: 587–591

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hofstra, R.M.W., Stelwagen, T., Pasini, B. et al. Ordering of markers in the pericentromeric region of chromosome 10. Hum Genet 96, 116–118 (1995). https://doi.org/10.1007/BF00214199

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00214199

Keywords

Navigation