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Two populations of somatostatin-immunoreactive neurons in the guinea pig striatum

Summary

Two populations of neurons displaying somatostatin-like immunoreactivity were detected immunohistochemically in the guinea pig striatum using a monoclonal antibody. Sparse, well-stained neurons similar to those described in other species were observed throughout the guinea pig caudate-putamen. These neurons contained both neuropeptide Y and NADPH-diaphorase in addition to somatostatin. A second large population of somatostatin immunoreactive neurons in which these other substances did not coexist was found within the putamen.

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Vincent, S.R., von Krosigk, M. Two populations of somatostatin-immunoreactive neurons in the guinea pig striatum. Cell Tissue Res. 252, 219–222 (1988). https://doi.org/10.1007/BF00213846

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  • DOI: https://doi.org/10.1007/BF00213846

Key words

  • Somatostatin (SRIF)
  • Striatum
  • Neuropeptides
  • Caudate-putamen
  • Immunohistochemistry
  • Guinea pig