Skip to main content

Advertisement

Log in

Restriction fragment length polymorphism of the gene of the human leukocyte integrin β-subunit (CD18)

  • Gene-Antigen Register
  • Published:
Immunogenetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Arnaout, M. A.: Leukocyte adhesion molecules deficiency: its structural basis, pathophysiology and implications for modulating the inflammatory response. Immunol Rev 114: 145–180, 1990

    Google Scholar 

  • Bell, G. I., Karam, J. H., and Rutter, W. J.: Polymorphic DNA region adjacent to the 5' end of the human insulin gene. Proc Natl Acad Sci USA 78: 5759–5763, 1981

    CAS  PubMed  Google Scholar 

  • Burmeister, M., Kim, S., Price, E. R., de Lange, T., Tantravahi, U., Myers, R. M., and Cox, D. R.: A map of the distal region of the long arm of human chromosome 21 constructed by radiation hybrid mapping and pulsed-field gel electrophoresis. Genomics 9: 19–30, 1991

    Google Scholar 

  • Cross, S. J., Edwards, J. H., Bentley, D. R., and Campbell, R. D.: DNA polymorphism of the C2 and factor B genes. Immunogenetics 21: 39–48, 1985

    Google Scholar 

  • Galt, J., Boyd, E., Connor, J. M., and Ferguson-Smith, M. A.: Isolation of chromosome-21 specific DNA probes and their use in the analysis of nondisjunction in Down syndrome. Hum Genet 81: 113–119, 1989

    Google Scholar 

  • Hogg, N. and Horton, M. A.: Myeloid antigens: new and previously defined clusters. In A. J. McMichael (ed.): Leukocyte typing III — white cell differentiation antigens, pp. 576–602, Oxford University Press, Oxford, 1987

    Google Scholar 

  • Kishimoto, T. K., Hollander, N., Roberts, T. M., Anderson, D. C., and Springer, T. A.: Heterogeneous mutations in the β subunit common to the LFA-1, Mac-1, and p150,95 glycoproteins cause leukocyte adhesion deficiency. Cell 50: 681–690, 1987

    Google Scholar 

  • Larson, R. S. and Springer, T. A.: Structure and function of leukocyte integrins. Immunol Rev 144: 181–217, 1990

    Google Scholar 

  • Law, S. K. A.: Restriction fragment length polymorphism of human CD18 (β-subunit of CR3/p150,95/LFA-1) gene. Complement Inflamm 6: 360, 1989

    Google Scholar 

  • Law, S. K. A., Gagnon, J., Hildreth, J. E. K., Wells, C. E., Willis, A. C., and Wong, A. J.: The primary structure of the β-subunit of the cell surface adhesion glycoproteins LFA-1, CR3, and p150,95 and its relationship to the fibronectin receptor. EMBO J 6: 915–919, 1987

    Google Scholar 

  • Marlin, S. D., Morton, C. C., Anderson, D. C., and Springer, T. A.: LFA-1 immunodeficiency disease — definition of the genetic defect and chromosomal mapping of α and β subunits of the lymphocyte function associated antigen 1 (LFA-1) by complementation in hybrid cells. J Exp Med 164: 855–867, 1986

    Google Scholar 

  • Meijer, H., Hamers, G. J. H., Jongbloed, R. J. E., Vaes-Peeters, G. P. M., van der Hulst, R. R. W. J., and Geraedts, J. P. M.: Distribution of meiotic recombination along nondisjunction chromosomes 21 in Down syndrome determined using cytogenetics and RFLP haplotyping. Hum Genet 83: 280–286, 1989

    Google Scholar 

  • Ruoslahti, E.: Integrins. J Clin Invest 87: 1–5, 1991

    Google Scholar 

  • Sanchez-Madrid, F., Nagy, J. A., Robbins, E., Simon, P. A., and Springer, T. A.: A human leukocyte differentiation antigen family with distinct alpha subunits and a common beta subunit: the lymphocyte function associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule. J Exp Med 158: 1785–1803, 1983

    Google Scholar 

  • Stewart, G. D., Tanzi, R. E., Kishimoto, T. K., Buraczynska, M., Haines, J. L., Drabkin, H., Gusella, J. F., Springer, T. A., Kurnit, D. M., and Van Keuren, M.: The CD18 gene maps to distal chromosome 21q22.3: RFLPs create a highly informative terminal haplotype. Am J Hum Genet 43s: A160, 1989

    Google Scholar 

  • Wells, C. E. and Law, S. K. A.: RFLP of the β-subunit of the cell surface adhesion glycoproteins. Complement Inflamm 4: 238, 1987

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Address correspondence and offprint requests to: S. K. A. Law.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Law, S.K.A., Taylor, G.M. Restriction fragment length polymorphism of the gene of the human leukocyte integrin β-subunit (CD18). Immunogenetics 34, 341–345 (1991). https://doi.org/10.1007/BF00211998

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00211998

Keywords

Navigation