Abstract
There have been recent reports of substantial increases occurring in the incidence of and/or mortality from tongue and mouth cancers in several countries. In this paper using data from Scotland (1960–89) we report on time trends in pharyngeal cancer. Similar increases in rates are evident for cancers of the oropharynx and hypopharynx while there has been little change in the occurrence of nasopharyngeal cancer (which has distinct aetiological factors). It therefore seems that reported changes in the incidence of and mortality from oral cancer may be real, and in Scotland, this is most probably due to changes in alcohol consumption.
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Andersson-AnvretM., ForsbyN., KleinG. and HenleW. (1978): The association between undifferentiated nasopharyngeal carcinoma and Epstein Barr virus shown by correlated nucleic acid hybridization and histopathological studies. In: de-The G. and Ito Y. (eds.) Nasopharyngeal carcinoma: etiology and control. Lyons: IARC Scientific Publication 20, pp. 347–357.
BoyleP. and RobertsonC. (1987): Statistical modelling of lung cancer and laryngeal cancer incidence data in 1960–1979 - Am. J. Epidemiol. 125: 731–744.
BoyleP., ZhengT., MacFarlaneG.J., McGinnR., MaisonneuveP., LaVecchiaC. and ScullyC. (1990): Recent advances in the etiology and epidemiology of head and neck cancer - Curr. Opin. Oncol. 2: 539–545.
BoyleP. and ParkinD.M. (1991): Statistical Methods for Registries. In: [Cancer Registration: Principles and Methods]: Jensen O.M., Parkin D.M., MacLennan R., Muir C.S. and Skeet R.G. (eds). International Agency for Research On Cancer - Publication No. 95, Lyons.
BrugereJ., QuenelP., LeclercA. and RodriguezJ. (1986): Differential effects of Tobacco and Alcohol in Cancer of the Larynx, Pharynx and Mouth - Cancer 57: 391–395.
DavisS. and SeversonR.K. (1987): Increasing incidence of cancer of the tongue in the United States among young adults - The Lancet i: 910–911.
DepueP. (1986): Rising Mortality from Cancer of the Tongue in Young White Males - N. Engl. J. Med. 315: 647.
De-TheG. (1982): Epidemiology of Epstein Barr virus and associated diseases. In: B. Roizman (ed.) The herpes-viruses - New York: Plenum Press, Vol. IA, pp. 25–103.
DollR., PayneP. and WaterhouseJ.A.H. (1966): Cancer Incidence in Five Continents, Volume I, Geneva: UICC.
DollR. and CookP. (1967): Summarising indices for comparison of Cancer Incidence Data - Int. J. Cancer 2: 269–279.
Keller A.Z. (1970): Cellular types, race, nativity, occupation, habits and associated diseases in the pathogenesis of lip cancer - Am. J. Epidem. 91: 486–499.
LindqvistC. and TeppoL. (1978): Epidemiological evaluation of sunlight as a risk factor of lip cancer -Br. J. Cancer 37: 983–989.
MacFarlaneG.J., BoyleP. and ScullyC. (1992): Oral Cancer in Scotland: changing incidence and mortality - Brit. Med. J. 305: 1121–1123.
MollerH. (1989): Changing incidence of cancer of the tongue, oral cavity and pharynx in Denmark - J. Oral. Pathol. Med. 18: 224–229.
MuirC., WaterhouseJ., MackT., PowellJ. and Whelan S. (ed.) (1987): Cancer Incidence in Five Continents Volume V. IARC Scientific Publication No. 88, Lyons: International Agency for Research on Cancer.
ParkinD.M., MuirC.S., WhelanS.L., GaoY.-T., FerlayJ. and PowellJ. (ed.) (1992): Cancer Incidence in Five Continents Volume VI. IARC Scientific Publication No. 120, Lyons: International Agency for Research On Cancer.
SpringJ.A. and BussD.H. (1977): Three centuries of alcohol in the British diet - Nature 270: 567–572.
TuynsA.J., EsteveJ., RaymondL., BerrinoF., BennamouE., BlanchetF., BoffettaP., CrosignaniP., DelMoralA., LehmannW., MerlettiF., PequignotG., RiboliE., Sancho-GarnierH., TerraciniB., ZubiriA. and ZubiriL. (1988): Cancer of the larynx/ hypopharynx, tobacco and alcohol: IARC international case-control study in Turin and Varese (Italy), Zagarossa and Navarra (Spain), Geneva (Switzerland) and Calvados (France) - Int. J. Cancer 41: 482–491.
UK Smoking Statistics (1991): Second Edition Wald N. and Nicholaides-Bouman A. (eds) - Oxford University Press, Oxford.
World Health Organization (WHO) (1977): Manual of the International Statistical Classification of Diseases, Injuries and Causes of Death (Ninth Revision), Geneva.
YoungT.B., FordC.N. and BrandenburgJ.H. (1986): An epidemiologic study of oral cancer in a Statewide network - Am. J. Otolaryngol. 7: 200–208.
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Macfarlane, G.J., Evstifeeva, T.V., Scully, C. et al. The descriptive epidemiology of pharyngeal cancer in Scotland. Eur J Epidemiol 9, 587–590 (1993). https://doi.org/10.1007/BF00211431
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DOI: https://doi.org/10.1007/BF00211431