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The MUC5AC gene: RFLP analysis with the Jer58 probe

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Abstract

We have recently obtained evidence that the locus corresponding to three groups of partial tracheobronchial cDNAs (A=Jer47, B=Jer57, C=Jer58) which mapped to chromosome 11p15 and was given the symbol MUC5 corresponds to two distinct genes which we have provisionally called MUC5B and MUC5AC. Here we describe the detection, using the Jer58 probe, which contains a 24-bp tandem repeat, of polymorphism in the MUC5AC gene with seven different restriction enzymes.

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References

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Authors and Affiliations

  1. Biologie et physiopathologie des cellules mucipares, U377 INSERM, Place de Verdun, F-59045, Lille Cedex, France

    P. Pigny, A. Laine, J. P. Aubert & N. Porchet

  2. Laboratoire de cytogénétique et génétique oncologiques, URA 1158 CNRS, Institut Gustave Roussy, F-94805, Villejuif Cedex, France

    V. C. Nguyen

  3. MRC Human Biochemical Genetics Unit, University College, NW1 2HE, London, UK

    W. S. Pratt & D. M. Swallow

  4. Laboratoire de Biochimie, USN A et Hôpital Huriez, CHRU de Lille, F-59037, Lille Cedex, France

    P. Pigny, A. Leclercq, J. P. Aubert & N. Porchet

Authors
  1. P. Pigny
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  2. W. S. Pratt
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  3. A. Laine
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  4. A. Leclercq
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  5. D. M. Swallow
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  6. V. C. Nguyen
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  7. J. P. Aubert
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  8. N. Porchet
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Pigny, P., Pratt, W.S., Laine, A. et al. The MUC5AC gene: RFLP analysis with the Jer58 probe. Hum Genet 96, 367–368 (1995). https://doi.org/10.1007/BF00210427

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  • DOI: https://doi.org/10.1007/BF00210427

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