Skip to main content
Log in

Localization of relaxin in human gestational corpus luteum

  • Short Communication
  • Published:
Cell and Tissue Research Aims and scope Submit manuscript

Summary

Corpora lutea from 12 pregnant women were prepared for immunohistochemical localization of relaxin using a highly specific antiserum. A positive response is given by luteal cells that are diffusely distributed throughout the corpus luteum. These cells do not form a distinctive group in any particular area. A negative response is seen in the adjacent ovarian tissue, and also in nongestational corpora lutea in an early luteal phase.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Anderson ML, Long JA, Hayashida T (1975) Immunofluorescence studies on the localization of relaxin in the corpus luteum of the pregnant rat. Biol. Reprod. 13:499–504

    Google Scholar 

  • Anderson ML, Long JA (1978) Localization of relaxin in the pregnant rat. Bioassay of tissue extracts and cell fractionation studies. Biol Reprod 18:110–117

    Google Scholar 

  • Kendall JZ, Plopper CG, Bryant-Greenwood GD (1978) Ultrastructural immunoperoxidase demonstration of relaxin in corpora lutea from a pregnant sow. Biol Reprod 18:94–98

    Google Scholar 

  • Larkin LH, Fields PA, Oliver RM (1977) Production of antisera against electrophoretically separated relaxin and immunofluorescent localization of relaxin in the porcine corpus luteum. Endocrinology 101:679–685

    Google Scholar 

  • Loumaye E, Teuwissen B, Thomas K. (1978) Characterization of relaxin radioimmunoassay using Bolton-Hunter reagent. Gynecol Obstet Invest 9:262–267

    Google Scholar 

  • Loumaye E, De Cooman S, Thomas K (1980) Immunoreactive relaxin-like substance in human seminal plasma. J Clin Endocr Metab 50:1142–1143

    Google Scholar 

  • O'Byrne EM, Carriere BT, Sorensen L, Segaloff A, Schwabe C, Steinetz BG (1978a) Plasma immunoreactive relaxin levels in pregnant and non-pregnant women. J Clin Endocrinol Metab 47:1106–1110

    Google Scholar 

  • O'Byrne EM, Flitcraft JF, Sawyer WK, Hochman J, Weiss G, Steinetz BG (1978b) Relaxin bioactivity and immunoactivity in human corpora lutea. Endocrinology 102:1641–1644

    Google Scholar 

  • Pages A (1955) Essai sur le système des cellules claires de Feyrter. Dehan édit. Montpellier

    Google Scholar 

  • Pearse AGE (1971) The endocrine polypeptide cells of the APUD series (structural and functional correlations). Mém Soc Endocrinol 19:543–556

    Google Scholar 

  • Pommerenke WT (1934) Experimental ligamentous relaxation in the guinea pig pelvis. Am J Obstet Gynecol 27:708–713

    Google Scholar 

  • Schwabe C, Steinetz B, Weiss G, Segaloff A, McDonald JK, O'Byrne E, Hochman J, Carriere B, Goldsmith L (1978) Relaxin. Recent Prog Horm Res 34:123–211

    Google Scholar 

  • Sherwood OD, O'Byrne EM (1974) Purification and characterization of porcine relaxin. Arch Biochem Biophys 160:185–196

    Google Scholar 

  • Sternberger LR (1974) Immunocytochemistry. Englewood Cliffs, New Jersey: Prentice-Hall, Inc.

    Google Scholar 

  • Sternberger LR, Hardy PH, Cueulis JJ, Meyer HG (1970) The unlabelled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen antibody complex (horseradish peroxidase — antihorseradish peroxidase) and its use in the identification of spirochetes. J Histochem Cytochem 18:315–333

    Google Scholar 

  • Thomas K, Loumaye E, Ferin J (1980) Relaxin in non-pregnant women during ovarian stimulation. Gynecol Obstet Invest 11:75–80

    Google Scholar 

  • Zarrow MX, O'Connor WB (1966) Localization of relaxin in the corpus luteum of the rabbit. Proc Soc Exp Biol Med 121:612–614

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mathieu, P., Rahier, J. & Thomas, K. Localization of relaxin in human gestational corpus luteum. Cell Tissue Res. 219, 213–216 (1981). https://doi.org/10.1007/BF00210030

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00210030

Key words

Navigation