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Polymorphism of the pentanucleotide repeat d(AAAAT) within intron 1 of the human tumor suppressor gene p53 (17p13.1)

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Abstract

DyeDeoxy terminator cycle sequencing of allele-specific polymerase chain reaction products has shown that there is a highly polymorphic d(AAAAT) pentanucleotide repeat within the first intron of the human p53 gene. This provides a genetic marker for tumor suppressor p53 gene alterations.

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References

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Authors and Affiliations

  1. Institut für Biochemie, FB 15, Justus-Liebig-Universität, Heinrich-Buff-Ring 58, D-35392, Giessen, Germany

    Meinhard Hahn & Alfred Pingoud

  2. Zentrum Biochemie, OE 4350, Medizinische Hochschule Hannover, D-30623, Hannover, Germany

    Rainer Fislage

Authors
  1. Meinhard Hahn
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  2. Rainer Fislage
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  3. Alfred Pingoud
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Hahn, M., Fislage, R. & Pingoud, A. Polymorphism of the pentanucleotide repeat d(AAAAT) within intron 1 of the human tumor suppressor gene p53 (17p13.1). Hum Genet 95, 471–472 (1995). https://doi.org/10.1007/BF00208983

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  • DOI: https://doi.org/10.1007/BF00208983

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