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Molecular basis of inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) polymorphism

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Abstract

A genetic polymorphism of the inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) was analyzed at the nucleic acid level. Three common alleles, ITIH1*1, ITIH1*2 and ITIH1*3, were characterized by mutations at codons 551 and 561 in exon 14. ITIH1*1 was characterized by GAG (Glu) at codon 551 and CAG (Gln) at codon 561, ITIH1*2, by GTG (Val) and CGG (Arg), and ITIH1*3, by GAG (Glu) and CGG (Arg).

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References

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Authors and Affiliations

  1. Department of Forensic Medicine, Yamagata University School of Medicine, 990-23, Yamagata, Japan

    M. Ding, K. Umetsu, A. Harada & T. Suzuki

  2. Department of Forensic Serology Faculty of Forensic Medicine, China Medical University, 11001, Shenyang, China

    M. Ding

  3. Department of Legal Medicine, Tottori University School of Medicine, 683, Yonago, Japan

    I. Yuasa

  4. Central Laboratory for Research and Education, Yamagata University School of Medicine, 990-23, Yamagata, Japan

    M. Sato

Authors
  1. M. Ding
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  2. K. Umetsu
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  3. I. Yuasa
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  4. M. Sato
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  5. A. Harada
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  6. T. Suzuki
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Ding, M., Umetsu, K., Yuasa, I. et al. Molecular basis of inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) polymorphism. Hum Genet 95, 435–436 (1995). https://doi.org/10.1007/BF00208970

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  • DOI: https://doi.org/10.1007/BF00208970

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