Summary
Clinically, the development of highly accurate imaging techniques that define adrenal anatomy and give information concerning adrenal physiology have revolutionized our approach to adrenal disorders [1, 2]. These techniques complement the highly accurate hormonal analyses that lead to the diagnosis of primary hyperaldosteronism, Cushing's syndrome, and pheochromocytoma. In addition, they help distinguish these entities from other adrenal disorders as well as other retroperitoneal processes. Thus, imaging techniques presently play a critical role in confirming the hormonal diagnosis and precisely localizing the specific adrenal lesion.
This article reviews the imaging techniques available and attempts to direct the reader to the procedure of choice for each adrenal disorder.
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References
Vaughan ED Jr, Carey RM (eds) (1989) Adrenal disorders. Thieme, New York
Scott HW Jr (1990) Surgery of the adrenal glands. Lippincott, Philadelphia
Conn JW (1955) Primary hyperaldosteronism — a new clinical entity. J Lab Clin Med 45:3
Vaughan ED Jr (1989) Diagnosis of adrenal disorders in hypertension. World J Urol 7:111
Vaughan ED Jr, Blumenfeld JD (1992) The adrenals. In: Walsh PC, Stamey TA, Retik AD, Vaughan ED Jr (eds) Campbell's urology, 6th edn. Saunders, Philadelphia, p 2360
Vaughan ED Jr, Atlas S, Carey RM (1989) Hyperaldosteronism. In: Vaughan ED JR, Carey RM (eds) Adrenal disorders. Thieme, New York, p 231
Neville AM, O'Hare NJ (1982) The human adrenal cortex pathology and biology: an integrated approach. Springer, New York
Kazam E, Engel IA, Zirinsky K, Auh YH, Rubenstein WA, Reckler JM, Markisz JA (1989) Sectional imaging of the adrenal gland — computerized tomography and ultrasound. In: Vaughan Ed Jr, Carey RM (eds) Adrenal disorders. Thieme, New York, p 37
Vaughan ED Jr (1991) Adrenal surgery. In: Marshall FF (eds) Operative urology. Saunders, Philadelphia, p 3
Siragy HM, Vaughan ED Jr, Carey RM (1989) Cushing's syndrome. In: Vaughan ED Jr, Carey RM (eds) Adrenal disorders. Thieme, New York, p 147
Vaughan ED Jr, Carey RM (1989) Adrenal carcinoma. In: Vaughan ED Jr, Carey RM (eds) Adrenal disorders. Thieme, New York
Sarkar SD, Cohen EL, Beierwaltes WH, Ice RD, Cooper R, Gold EM (1977) A new and superior adrenal imaging agent: [131I]-6B-iodomethyl-19-norcholesterol (np-59) evaluation in humans. J Clin Endocrinol Metab 45:353
Kazerooni EA, Sisson JC, Shapiro et al (1990) Diagnostic accuracy and pitfalls of (iodine-131) 6-beta-iodomethyl-119-norcholesterol (np-59) imaging. J Nucl Med 31:526
Mitty HA, Cohen BA (1985) Adrenal imaging. Urol Clin North Am 12:771
Mitty HA, Yeh HC (1982) Radiology of the adrenals for sonography and CT. Saunders, Philadelphia
Huebener KH, Treugut TH (1984) Adrenocortical dysfunction: CT findings. Radiology 150:195
Bellegrun A, de Kernion JB (1989) What to do about the incidentally found adrenal mass. World J Urol 7:117
Reinig JW, Doppman JL, Dwyer AJ et al (1986) MRI of indeterminate renal masses. AJR 147:493
Reinig JW, Doppman JL, Dwyer AJ, Johnson AR, Knop RH (1986) Adrenal masses differentiated by MR. Radiology 158:81
Hussain S, Belldegrun A (1985) Differentiation of malignant from benign adrenal masses: predictive indices on computer tomography. AJR 144:61
Glazer GM, Zwoolsey EJ, Borrello J et al (1986) Adrenal tissue characterization using MR imaging. Radiology 158:73
Glazer GM (1988) MR imaging of the liver, kidneys, and adrenal glands. Radiology 166:303–312
Chezmar JL, Robbins SM, Nelson RC, Steinberg HV, Torres WE, Bernardino ME (1988) Adrenal masses: characterization with T1 weighted MR imaging. Radiology 166:357
Paling MR, Brookeman JR, Mugler JP (1987) Tumor detection with phase-contrast imaging: an evaluation of clinical potential. Radiology 162:199–203
Ross NS, Aron DC (1990) Hormonal evaluation of the patient with an incidentally discovered adrenal mass. N Engl J Med 323:1401
Chang GA, Glazer HS, Lee JKT et al (1987) Adrenal gland: MR imaging. Radiology 163:123
Quint LE, Glazer GM, Francis IR, Shapiro B, Cherevert TL (1987) Pheochromocytoma and paraganglioma: comparison of MR imaging with CT and I-131 MIBG scintigraphy. Radiology 165:89–93
Counsel for Scientific Affairs (1989) Report of a panel on magnetic resonance imaging: magnetic resonance imaging of the abdomen and pelvis. JAMA 261:420
Doppman JL, Reinig JW, Dwyer AJ et al (1987) Differentiation of adrenal masses by magnetic resonance imaging. Surgery 102:1018–1026
Papavasiliou C, Gouliamos A, Deligiorgi E, Vlahos L, Cambouris T (1990) Masses of myeloadipose tissue: radiological and clinical considerations. Int J Radiat Oncol Biol Phys 19:985–993
Amberson JB, Gray GF (1989) Adrenal pathology. In: Vaughan ED Jr, Carey RM (eds) Adrenal disorders. Thieme, New York, p 13
Melicow NM (1977) 100 cases of pheochromocytoma (107 tumors) at the Columbia-Presbyterian Medical Center, 1926–1976. A clinicopathological analysis. Cancer 40:1987–2004
Fink IJ, Reinig JW, Dwyer AJ (1985) MR imaging of pheochromocytomas. J Comput Assist Tomogr 9:454–458
Manger WM, Gifford RW Jr (1990) Pheochromocytoma. In: Laragh JH, Brenner BM (eds) Hypertension pathophysiology, diagnosis and management. Raven, New York, pp 1639–1660
Reckler JM, Vaughan ED Jr, Tjeuw M, Carey RM (1989) Pheochromocytoma. In: Vaughan ED Jr, Carey RM (eds) Adrenal disorders. Thieme, New York, p 259
Shapiro B, Copp JE, Sisson JC, Ayer TL, Wallis J, Beierwaltes WH (1985) Iodine-131 metaiodobenzylguanidine for the localization of suspected pheochromocytoma: experience in 400 cases. J Nucl Med 26:576
Deal JE, Seaver PS, Barrett TM, Dillon MJ (1990) Pheochromocytoma — Investigation and management of 10 cases. Arch Dis Child 65:269–274
Dietrich RB, Cangarloo H, Lenarsky C (1987) Neuroblastoma: the role of MR imaging. AJR 148:937–942
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Vaughan, E.D. Imaging of the adrenal gland. World J Urol 10, 190–197 (1992). https://doi.org/10.1007/BF00208908
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DOI: https://doi.org/10.1007/BF00208908