Abstract
Liver hamartomas in tuberous sclerosis (TS) have been uncommonly documented compared with hamartomatous lesions in other organs. We prospectively studied by US 21 patients that fulfilled the established criteria of TS, looking for hepatic and renal lesions. Nine patients (43 %) showed multiple, rounded hyperechoic liver lesions. Of these patients, 8 were also studied with CT showing several round low-density fatty lesions. Multiple hyperechoic renal lesions similar to those described in the liver were present in 17 patients (81 %). Fat-containing tumors in the liver in TS have been described as liver hamartomas. We believe, considering the high prevalence of liver hamartomas in patients with TS and the scarcity of fat-containing lesions in the general population, that their presence should be considered as a criterion of TS, even in the absence of histological confirmation.
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Galant, J., Martí-Bonmatí, L., Ripollés, T. et al. Hepatic manifestations of tuberous sclerosis studied by US and CT. Eur. Radiol. 5, 486–491 (1995). https://doi.org/10.1007/BF00208339
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DOI: https://doi.org/10.1007/BF00208339