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Microskin grafting with Biobrane: a new application

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Abstract

A new grafting technique involving the combination of skin micrografts and Biobrane is reported. This is a modification of a method originally reported from China, utilising cadaveric allograft and skin micrografts. Experiments to verify the technique were carried out in a pig model. Small split-thickness skin autografts were finely minced into tiny particles and evenly spread on Biobrane. The micrografts with Biobrane were transplanted to controlled wounds in pigs. The expansion ratios of the micrografts were 10:1, they took well and the healing time of the wound was from 35–46 days. Based on successful animal experiments, we have used this technique successfully to treat severely burned patients.

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Wang, N.Z., Reynolds, P.S., Coumbe, A. et al. Microskin grafting with Biobrane: a new application. Eur J Plast Surg 18, 157–161 (1995). https://doi.org/10.1007/BF00207560

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  • DOI: https://doi.org/10.1007/BF00207560

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