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Factual, statistical and logical issues in the search for a paternal age effect for Down syndrome

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References

  • Carothers A (1989) Controversy concerning paternal age effect in 47,+21 Down's syndrome. Hum Genet 78:384–385

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  • Cross PK, Hook EB (1987) An analysis of paternal age and 47,+21 in 35,000 new prenatal cytogenetic diagnosis data from the New York State Chromosome Registry: no significant effect. Hum Genet 77:307–313

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  • Hook EB (1987) Issues in analysis of data on paternal age and 47,+21: implications for genetic counseling for Down's syndrome. Hum Genet 77:303–306

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Authors and Affiliations

  1. School of Public Health, University of California, 94720, Berkeley, CA, USA

    Ernest B. Hook

  2. New York State Department of Health, Bureau of Environmental and Occupational Epidemiology, 12237, Albany, NY, USA

    Philip K. Cross

  3. Department of Mathematics and Statistics, University of Minnesota, 55812, Duluth, MN, USA

    Ronald R. Regal

Authors
  1. Ernest B. Hook
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  2. Philip K. Cross
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  3. Ronald R. Regal
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Hook, E.B., Cross, P.K. & Regal, R.R. Factual, statistical and logical issues in the search for a paternal age effect for Down syndrome. Hum Genet 85, 387–388 (1990). https://doi.org/10.1007/BF00206769

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  • DOI: https://doi.org/10.1007/BF00206769

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