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An HhaI polymorphism is present in factor IX genes of Asian subjects

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Summary

Hemophilia B is caused by decreased factor IX procoagulant activity. An HhaI restriction site polymorphism near the factor IX gene has been detected by the polymerase chain reaction. Frequency and linkage data already observed in Caucasians are confirmed and the polymorphism is also prevalent in the factor IX genes of Black and Asian populations.

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References

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Authors and Affiliations

  1. Puget Sound Blood Center, 98104, Seattle, WA, USA

    Alexander P. Reiner & Arthur R. Thompson

  2. The University of Washington, 98104, Seattle, WA, USA

    Alexander P. Reiner & Arthur R. Thompson

Authors
  1. Alexander P. Reiner
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  2. Arthur R. Thompson
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Reiner, A.P., Thompson, A.R. An HhaI polymorphism is present in factor IX genes of Asian subjects. Hum Genet 86, 87–88 (1990). https://doi.org/10.1007/BF00205181

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  • DOI: https://doi.org/10.1007/BF00205181

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