Summary
Plasminogen (PLG) phenotyping has been performed on 450 unrelated individuals from northern Japan, using wide-scale ultrathin layer polyacrylamide gel isoelectric focusing combined with immunoblotting. One common phenotype and six rare ones were observed. The rare phenotypes included the recently detected allele PLG*M6 in a new combination with PLG*M5 allele. The estimated allele frequencies for PLG*A, PLG*A3, PLG*M2, PLG*M5, PLG*M6, PLG*B, and PLG*B2 were 0.961, 0.009, 0.001, 0.016, 0.001, 0.003, and 0.009, respectively.
Zusammenfassung
Der genetische Polymorphismus des Plasminogen (PLG) wurde mit Hilfe der Isoelektrofokussierung und des Immunoblotting in einer Stichprobe von 450 nicht verwandten Personen aus der nördlichen Region Japans untersucht. Die folgende Allelfrequenzen wurden ermittelt: PLG*A = 0.961, PLG*A3 = 0.009, PLG*M2 = 0.001, PLG*M5 = 0.016, PLG*M6 = 0.001, PLG*B = 0.003 und PLG*B2 = 0.009.
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Sebetan, I.M., Aoki, Y. & Funayama, M. Plasminogen (PLG) polymorphism in northern Japanese: Confirmation of PLG*M6 allele. Z Rechtsmed 103, 43–45 (1989). https://doi.org/10.1007/BF00203942
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DOI: https://doi.org/10.1007/BF00203942