Skip to main content
SpringerLink
Log in

Suppression of spin diffusion in selected frequency bands of nuclear Overhauser spectra

  • Short Communications
  • Published:
Journal of Biomolecular NMR Aims and scope Submit manuscript

    We’re sorry, something doesn't seem to be working properly.

    Please try refreshing the page. If that doesn't work, please contact support so we can address the problem.

Summary

A variant of two-dimensional nuclear Overhauser effect spectroscopy (NOESY) is described that yields information about cross-relaxation rates between pairs of spins, while the migration of magnetization through several consecutive steps (spin diffusion via neighboring spins) is largely suppressed. This can be achieved by inserting a doubly-selective inversion pulse in a conventional NOESY sequence.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Anil, Kumar, Ernst, R.R. and Wüthrich, K. (1980) Biochem. Biophys. Res. Commun., 95, 1–6.

    Google Scholar 

  • Anil, Kumar, Wagner, G., Ernst, R.R. and Wüthrich, K. (1981) J. Am. Chem. Soc., 103, 3654–3658.

    Google Scholar 

  • Boelens, R., Koning, T.M.G. and Kaptein, R. (1988) J. Mol. Struct., 173, 299–311.

    Google Scholar 

  • Borgias, B.A. and James, T.L. (1988) J. Magn. Reson., 79, 493–512.

    Google Scholar 

  • Boulat, B., Burghardt, I. and Bodenhausen, G. (1992) J. Am. Chem. Soc., 114, 10679.

    Google Scholar 

  • Burghardt, I., Konrat, R., Boulat, B., Vincent, S.J.F. and Bodenhausen, G. (1993) J. Chem. Phys., 98, 1721–1736.

    Google Scholar 

  • Drew, H.R., Wing, R.M., Takano, T., Broka, C., Tanaka, S., Itakura, K. and Dickerson, R.E. (1981) Proc. Natl. Acad. Sci. USA, 78, 2179–2183.

    Google Scholar 

  • Emsley, L. and Bodenhausen, G. (1992) J. Magn. Reson., 97, 135–148.

    Google Scholar 

  • Fejzo, J., Krezel, A.M., Westler, W.M., Macura, S. and Markley, J.L. (1991) J. Magn. Reson., 92, 651–657.

    Google Scholar 

  • Fejzo, J., Westler, W.M., Markley, J.L. and Macura, S. (1992) J. Am. Chem. Soc., 114, 1523–1524.

    Google Scholar 

  • Grzesiek, S. and Bax, A. (1993) J. Am. Chem. Soc., 115, 12593–12594.

    Google Scholar 

  • Kalk, A. and Berendsen, H.J.C. (1976) J. Magn. Reson. 24, 343–366.

    Google Scholar 

  • Lane, A.N. (1988) J. Magn. Reson., 78, 425–439.

    Google Scholar 

  • Macura, S., Westler, W.M. and Markley, J.L. (1994) Methods Enzymol., 239, 106–144.

    Google Scholar 

  • MassefskiJr., W. and Redfield, A.G. (1988) J. Magn. Reson., 78, 150–155.

    Google Scholar 

  • Neuhaus, D. and Williamson, M. (1989) The Nuclear Overhauser Effect in Structural and Conformational Analysis, VCH, Weinheim.

    Google Scholar 

  • Piotto, M., Saudek, V. and Sklenář, V. (1992) J. Biomol. NMR 2, 661–665.

    Google Scholar 

  • Schwager, M. and Bodenhausen, G. (1996) J. Magn. Reson. Ser. B, in press.

  • Sklenář, V., Piotto, M., Leppik, R. and Saudek, V. (1993) J. Magn. Reson. Ser. A, 102, 241–245.

    Google Scholar 

  • Withka, J.M., Swaminathan, S., Beveridge, D.L. and Bolton, P.H. (1991) J. Am. Chem. Soc., 113, 5041–5049.

    Google Scholar 

  • Zwahlen, C., Vincent, S.J.F., Di, Bari, L., Levitt, M.H. and Bodenhausen, G. (1994) J. Am. Chem. Soc., 116, 362–368.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National High Magnetic Field Laboratory, Center for Interdisciplinary Magnetic Resonance, 1800 E. Paul Dirac Drive, 32310, Tallahassee, FL, USA

    Sébastien J. F. Vincent, Catherine Zwahlen & Geoffrey Bodenhausen

  2. Department of Chemistry, Florida State University, 32306, Tallahassee, FL, USA

    Geoffrey Bodenhausen

Authors
  1. Sébastien J. F. Vincent
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Catherine Zwahlen
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Geoffrey Bodenhausen
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Vincent, S.J.F., Zwahlen, C. & Bodenhausen, G. Suppression of spin diffusion in selected frequency bands of nuclear Overhauser spectra. J Biomol NMR 7, 169–172 (1996). https://doi.org/10.1007/BF00203828

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00203828

Keywords

Search

Navigation