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Verhalten des 5-Hydroxy-tryptamin und der 5-Hydroxyindol-Essigsäure im Zusammenhang mit der Agonie (I.)

Study of 5-HT and 5-HIAA in relation to the length of agonic suffering

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Summary

The authors have studied the levels of 5-HT and 5-HIA,—in serum, CSP fluid and pericardial fluid of cadavers at the Forensic Anatomic Institute of Granada and its relations with the length of agonic suffering. The results showed us that the study of 5-HT and its main metabolite, the 5-HIAA, may be useful for the exact evaluation of agonic suffering, and the pericardial fluid is most suited for the analysis of 5-HT and 5-HIAA.

We found that there was a significant correlation between the 5-HT and 5-HIAA and the agonic suffering. When the agonic sufferings of a moderate length (10 min-6h) were compared with the slow and long processes of death, the correlation was highly significant (P<0.001).

Zusammenfassung

Wir haben die 5-Hydroxy-tryptamin- und 5-Hydroxyindol-Essigsäure-Werte im Serum, in der Cerebrospinalflüssigkeit und in der Perikard-Flüssigkeit aus gerichtlichen Leichen, die im Anatomischen Institut für Rechtsmedizin in Granada obduziert wurden, und den Zusammenhang mit der Dauer der Agonie untersucht. Die Ergebnisse erlauben uns zu behaupten, daß die Bestimmung des 5-Hydroxy-tryptamin und seines wichtigen Metabolits, der 5-Hydroxy-indol-Essigsäure, große Möglichkeiten für die genaue Bewertung der Agonie eröffnet. Ideal ist die Bestimmung in der Perikard-Flüssigkeit.

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Authors and Affiliations

  1. Departamento de Medicina Legal, Universidad de Granada, Faculdad de Medicina, Avenida de Madrid S/N, Granada, Spanien

    A. Luna, E. Villanueva, C. Hernandez-Cueto & J. D. Luna

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  1. A. Luna
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  2. E. Villanueva
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  3. C. Hernandez-Cueto
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  4. J. D. Luna
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Luna, A., Villanueva, E., Hernandez-Cueto, C. et al. Verhalten des 5-Hydroxy-tryptamin und der 5-Hydroxyindol-Essigsäure im Zusammenhang mit der Agonie (I.). Z Rechtsmed 89, 215–226 (1983). https://doi.org/10.1007/BF00203725

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  • DOI: https://doi.org/10.1007/BF00203725

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