Summary
Silver-stained synaptonemal complexes in surface-spread pachytene nuclei from a man, heterozygous for a reciprocal translocation, were analysed by electron microscopy. Contrary to the classically expected cross-shaped configuration, extensive non-homologous pairings were observed with asymetrical association in the lateral elements of the non-homologous arms of the quadrivalents. A possible role of the heterosynapsis in reproductive failure is discussed.
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de Perdigo, A., Gabriel-Robez, O., Ratoinponirina, C. et al. Synaptonemal complex analysis in a human male carrier of a 4;6 translocation: heterosynapsis without previous homosynapsis. Hum Genet 86, 279–282 (1991). https://doi.org/10.1007/BF00202409
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DOI: https://doi.org/10.1007/BF00202409