Abstract
Linkage analysis in 19 families with autosomal recessive polycystic kidney disease (ARPKD) has shown that ARPKD is not linked to the recently assigned second gene locus for autosomal dominant polycystic kidney disease (ADPKD) on chromosome 4q (PKD2). Thus, there is strong evidence that ADPKD and ARPKD have different gene loci.
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Zerres, K., Mücher, G. & Rudnik-Schöneborn, S. Autosomal recessive polycystic kidney disease does not map to the second gene locus for autosomal dominant polycystic kidney disease on chromosome 4. Hum Genet 93, 697–698 (1994). https://doi.org/10.1007/BF00201574
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DOI: https://doi.org/10.1007/BF00201574