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Effect of chronic endosulfan treatment on pharmacological actions of diazepam in rats

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References

  1. Agarwal DK, Seth PK, Gupta PK (1978) Effect of endosulfan on drug metabolizing enzymes and lipid peroxidation in rat. J Environ Sci Health C13:49–62.

    Google Scholar 

  2. Aleksandrowicz R (1979) Endosulfan poisoning and chronic brain syndrome. Arch Toxicol 43: 65–68.

    Google Scholar 

  3. Butcher LL, Engle J, Fuxe K (1972) Behavioural, biochemical and histochemical analysis of the central effects of monoamine precursors after peripheral decarboxylase inhibition. Brain Res 41: 387–411.

    Google Scholar 

  4. Dorough HW, Huhtanen K, Marhsall TC, Bryant HE (1978) Fate of endosulfan in rats and toxicological consideration of apolar metabolites. Pest Biochem Physiol 8: 241–252.

    Google Scholar 

  5. Dunham NW, Miya TS (1957) A note on a simple apparatus for detecting neuorlogical deficit in rats and mice. J Am Pharmaceutical Assoc Sci Edi IXVI: 208–209.

    Google Scholar 

  6. Ely TD, Macfarlane JW Galen WP, Hine CH (1976) convulsions in Thioden workers. A preliminary report. J Occup Med 9: 35–37.

    Google Scholar 

  7. Gupta PK (1976) Endosulfan-induced neurotoxicity in rats and mice. Bull Environ Contam Toxicol 15: 708–713.

    Google Scholar 

  8. Gupta PK, Gupta RC (1977) Influence of endosulfan on pentobarbitone sleeping time and blood and brain concentration in male rats. J. Pharm Pharmacol 29: 245–246.

    Google Scholar 

  9. Mason DFG (1964) Hypnotics and General Anaesthetics. In: Laurence DR, Bacharach AL (eds) Evaluation of drug activities: Pharmacometrics, vol.1, Academic Press,

  10. Mennini R, Caccia S, Garattini S (1987) Mechanism of action of anxiolytic drugs. Prog Drug Res 31: 315.

    Google Scholar 

  11. Randall LO, Kappel B (1973) Pharmacological activity of some benzodiazepines. In: Garattini S, Mussini E, Randoll LO (eds) The benzodiazepines, Raven Press, New York, p. 27.

    Google Scholar 

  12. Schwartz MA, Bommer P, Vane FM (1967) diazepam metabolites in the rat: characterization by high resolution mass spectrometry and nuclear magnetic resonance. Arch Biochem Biophys 121: 508–516.

    Google Scholar 

  13. Singh SK, Pandey RS (1989) Differential effects of chronic endosulfan exposure to male rats in relation to hepatic drug metabolism and androgen biotransformation. Ind J Biochem Biphys 256: 262–267.

    Google Scholar 

  14. Tyagi SR, Singh Y, Srivastava PK, Misra UK (1984) Induction of hepatic mixed function oxidase system by endosulfan in rats. Bull Environ Contam Toxicol 32: 550–556.

    Google Scholar 

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Correspondence to Vanaja Paul.

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Paul, V., Kazi, M., Balasubramaniam, E. et al. Effect of chronic endosulfan treatment on pharmacological actions of diazepam in rats. Bull. Environ. Contam. Toxicol. 51, 18–23 (1993). https://doi.org/10.1007/BF00200995

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Keywords

  • Waste Water
  • Water Management
  • Water Pollution
  • Diazepam
  • Pharmacological Action